{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T12:48:54Z","timestamp":1781700534316,"version":"3.54.5"},"reference-count":28,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2019,5,10]],"date-time":"2019-05-10T00:00:00Z","timestamp":1557446400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>The purpose of this manuscript is to investigate the treatment of skin soft tissue embolization or vascular occlusion after the injection of hyaluronic acid (HA) for Injection Rhinoplasty (IR) in Asians with a special interest in the time occurrence of the occlusion.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 35 cases were evaluated after receiving HA injections for IR who presented with a vascular occlusive event. They were divided into three stages based on the time to embolization. Immediate, \u22645\u00a0hours; early, \u22643\u00a0days; and late, &gt;3\u00a0days. There were two cases of immediate, 28 deemed early, and five late. Methods to prevent tissue necrosis are reviewed in the manuscript based on these stages.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Skin color gradually recovered to normal after 11 treatments in 11 patients with mild embolization. No ischemic aggravation or skin necrosis was observed in 19 patients with moderate embolization; red scarring was seen in two and hypertrophic scar with uneven skin color in one patient. The five patients in the severe category had longer healing, more red scars, and more hypertrophic scarring.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The treatment of skin soft tissue embolization or vascular occlusion after HA IR in Asians can be effected by identifying the stage and degree of embolization and treating appropriately with the outlines presented in this manuscript.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.12968","type":"journal-article","created":{"date-parts":[[2019,5,10]],"date-time":"2019-05-10T08:49:45Z","timestamp":1557478185000},"page":"747-754","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Treatment of skin soft tissue embolism after hyaluronic acid injection for injection rhinoplasty in Asian patients"],"prefix":"10.1111","volume":"18","author":[{"given":"Hua\u2010Wei","family":"Ouyang","sequence":"first","affiliation":[{"name":"Department of Plastic &amp; Laser Cosmetic Hunan Provincial People's Hospital Changsha China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gao\u2010Feng","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Plastic &amp; Laser Cosmetic Hunan Provincial People's Hospital Changsha China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Plastic &amp; Laser Cosmetic Hunan Provincial People's Hospital Changsha China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Lei","sequence":"additional","affiliation":[{"name":"Department of Plastic &amp; Laser Cosmetic Hunan Provincial People's Hospital Changsha China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5183-5433","authenticated-orcid":false,"given":"Michael H.","family":"Gold","sequence":"additional","affiliation":[{"name":"Gold Skin Care Center Nashville Tennessee"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Tan","sequence":"additional","affiliation":[{"name":"Department of Plastic &amp; Laser Cosmetic Hunan Provincial People's Hospital Changsha China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,5,10]]},"reference":[{"issue":"6","key":"e_1_2_7_2_1","first-page":"378\u2010379","article-title":"The application of hyaluronic acid in the beauty of the eyes","volume":"28","author":"Bai Y\u2010J","year":"2017","journal-title":"Chin J Aesth Plast Surg"},{"issue":"3","key":"e_1_2_7_3_1","first-page":"164","article-title":"Ideal injection dose for cosmetics injection","volume":"21","author":"Wang NA","year":"2010","journal-title":"Chin J Aesth Plast Surg"},{"issue":"5","key":"e_1_2_7_4_1","first-page":"265","article-title":"Retrospective analysis of complication of hyaluronic acid fillers injection and its treatments","volume":"25","author":"Zhao P","year":"2014","journal-title":"Chin J Aesth Plast Surg"},{"key":"e_1_2_7_5_1","unstructured":"The International Society of Aesthetic Plastic Surgery.Highlights of the ISAPS 2014 statistics on cosmetic surgery.http:\/\/www.isaps.org\/Media\/Default\/global-statistics\/Quick%20Facts%202015v2.pdf. 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