{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T09:42:23Z","timestamp":1790242943392,"version":"4.1.0"},"reference-count":25,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2019,6,13]],"date-time":"2019-06-13T00:00:00Z","timestamp":1560384000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2020,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Hirsutism is a common clinical condition encountered in day\u2010to\u2010day practice. The androgenic causes account for more than 80% of these patients and include polycystic ovary syndrome (PCOS), which affects about 70%\u201080% of hirsute women. The second most common cause is idiopathic hirsutism. Omentin\u20101 is an adipokine mainly produced by visceral adipose tissue.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>The current study aimed at evaluating omentin\u20101 levels in hirsute females with PCOS and in idiopathic hirsutism.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients and Methods<\/jats:title><jats:p>Eighty\u2010five females were included in this study. They were classified into three groups: thirty hirsute patients with PCOS, thirty females with idiopathic hirsutism, and twenty\u2010five healthy control females. The participants were subjected to history taking, physical and dermatological examination. A gynecological history and radiological examination of the ovary also were done. Serum testosterone and omentin\u20101 were measured by ELISA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Serum testosterone was statistically elevated in PCOS than other groups. Serum omentin\u20101 in females with idiopathic hirsutism was statistically significantly higher than control and PCOS. There was a significant inverse correlation between serum testosterone level and serum omentin\u20101 level.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Omentin\u20101 may be involved in the pathogenic process of hirsutism.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.13043","type":"journal-article","created":{"date-parts":[[2019,6,13]],"date-time":"2019-06-13T07:58:11Z","timestamp":1560412691000},"page":"535-539","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Evaluation of serum level of omentin\u20101 in females with hirsutism"],"prefix":"10.1111","volume":"19","author":[{"given":"Mohammed Z.","family":"Kenawi","sequence":"first","affiliation":[{"name":"Department of Dermatology, Venereology &amp; Andrology, Faculty of Medicine Benha University Benha Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9579-1727","authenticated-orcid":false,"given":"Essam M.","family":"Akl","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology &amp; Andrology, Faculty of Medicine Benha University Benha Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jehan H.","family":"Sabry","sequence":"additional","affiliation":[{"name":"Department of Clinical Pathology, Faculty of Medicine Benha University Benha Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara T.","family":"Mostafa","sequence":"additional","affiliation":[{"name":"Department of Obstetric &amp; Gynecology, Faculty of Medicine Benha University Benha Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,6,13]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40257-014-0078-4"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-1241.2007.01621.x"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apnu.2013.02.003"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(02)02725-4"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.3109\/09513591003686353"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.00572.2004"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.114.120410"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijt.ijt_93_16"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2003.10.004"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmr042"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1590\/0004-2730000002923"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1159\/000355356"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2008.09.003"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.3109\/09513590.2014.888412"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvw016"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2010.02.053"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13287-017-0676-1"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/368970"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijd.12362"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.018689"},{"key":"e_1_2_9_22_1","first-page":"5477","article-title":"Long non\u2010coding RNA regulates hair follicle stem cell proliferation and differentiation through PI3K\/AKT signal pathway","volume":"17","author":"Cai B","year":"2018","journal-title":"Mol Med Rep"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1529-8019.2008.00214.x"},{"key":"e_1_2_9_24_1","first-page":"24","article-title":"Race, rather than skin pigmentation, predicts facial hair growth in women","volume":"7","author":"Javorsky E","year":"2014","journal-title":"J Clin Aesthet Dermatol"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-10-0205"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.2174\/1570161112999140217095038"}],"container-title":["Journal of Cosmetic Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.13043","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jocd.13043","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.13043","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,21]],"date-time":"2023-08-21T19:32:25Z","timestamp":1692646345000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jocd.13043"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6,13]]},"references-count":25,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,2]]}},"alternative-id":["10.1111\/jocd.13043"],"URL":"https:\/\/doi.org\/10.1111\/jocd.13043","archive":["Portico"],"relation":{},"ISSN":["1473-2130","1473-2165"],"issn-type":[{"value":"1473-2130","type":"print"},{"value":"1473-2165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,6,13]]},"assertion":[{"value":"2018-11-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-05-20","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-06-13","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}