{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T12:40:20Z","timestamp":1782996020048,"version":"3.54.5"},"reference-count":7,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,6,26]],"date-time":"2019-06-26T00:00:00Z","timestamp":1561507200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Facial and neck skin tightening, and rejuvenation began decades ago with maximally invasive incisional face\u2010lift surgery. Aesthetic trends, patient demands, and innovative technology brought about minimally invasive and noninvasive interventions\u2014such as radiofrequency, ultrasound, laser and intense pulsed light as well as dermal fillers and other injectables\u2014to address facial and neck skin laxity. These procedures reduce facial and neck skin laxity with less risk and less downtime than maximally invasive face\u2010lift or face\u2010lift plus liposuction; however, these interventions are often deemed to offer reduced results.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>To evaluate the safety and efficacy\u2014as well as patient satisfaction\u2014of Rotational Fractional Resection (RFR) in subjects with mild\u2010to\u2010moderate submental fat and mild\u2010to\u2010moderate submental skin laxity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials<\/jats:title><jats:p>Rotational fractional resection with the Nuvellus (Recros, Inc) platform, which uses 1.5 mm in diameter rotating scalpels\u2014termed scalpets\u2014to resect lax skin followed by a rotating cannulas to perform focal lipectomy through resected access ports.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Thirtyone patients were evaluated 30 days after RFR, in an ongoing prospective, multi\u2010center, nonrandomized study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The majority of subjects had a \u22651\u2010grade improvement in investigator\u2010evaluated skin laxity and lipodystrophy; 84% of subjects were satisfied with their neck and jawline appearance and 97% of subjects they would likely recommend the procedure. Minimal procedural and post\u2010procedural pain, minimal scarring in 94% of subjects, and no severe skin\u2010related adverse effects.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Rotational fractional resection is essentially a new concept that has a risk and side effect profile that is comparable or better than\u2010surgical skin tightening, with measurable permanent results approaching that of surgical skin tightening. This investigational procedure advances the evolution of facial and neck aesthetic procedures with results approaching those of surgery in a single treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Early RFR results are promising but, yet to be conclusive. However current outcome reports identify a procedure that meet patient demands for a minimally invasive office\u2010 based procedure to look better with limited downtime.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.13057","type":"journal-article","created":{"date-parts":[[2019,6,27]],"date-time":"2019-06-27T06:24:46Z","timestamp":1561616686000},"page":"1182-1185","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Aesthetic evolution drives birth of minimally invasive surgery subgroup"],"prefix":"10.1111","volume":"18","author":[{"given":"Steve","family":"Dayan","sequence":"first","affiliation":[{"name":"Department of Otolaryngology University of Illinois Chicago Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,6,26]]},"reference":[{"key":"e_1_2_8_2_1","unstructured":"American Society for Aesthetic Plastic Surgery (ASAPS).Cosmetic surgery national data bank statistics. 2017. Available at:https:\/\/surgery.org\/sites\/default\/files\/ASAPS-Stats2017.pdf"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0033-1363756"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4419-1093-6_2"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cps.2011.05.003"},{"key":"e_1_2_8_6_1","unstructured":"American Society of Plastic Surgeons (ASPS).Neck lift. 2018. Available at:https:\/\/www.plasticsurgery.org\/cosmetic-procedures\/neck-lift"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.asj.2007.12.009"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.2147\/CCID.S69118"}],"container-title":["Journal of Cosmetic Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjocd.13057","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.13057","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jocd.13057","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.13057","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T17:38:40Z","timestamp":1694021920000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jocd.13057"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6,26]]},"references-count":7,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2019,10]]}},"alternative-id":["10.1111\/jocd.13057"],"URL":"https:\/\/doi.org\/10.1111\/jocd.13057","archive":["Portico"],"relation":{},"ISSN":["1473-2130","1473-2165"],"issn-type":[{"value":"1473-2130","type":"print"},{"value":"1473-2165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,6,26]]},"assertion":[{"value":"2019-04-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-04-26","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-06-26","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}