{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T21:02:30Z","timestamp":1770066150965,"version":"3.49.0"},"reference-count":25,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2019,9,26]],"date-time":"2019-09-26T00:00:00Z","timestamp":1569456000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2020,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Growing evidence supports skin cooling (cryoanalgesia) or skin vibration (vibroanalgesia) as potential techniques for pain alleviation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>To compare the effect of skin vibration using the Buzzy<jats:sup>\u00ae<\/jats:sup> vibration device with that of skin cooling for 2\u00a0minutes, as methods to reduce the pain of 1% lidocaine\u2010epinephrine infiltration.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods &amp; Materials<\/jats:title><jats:p>Sixty healthy volunteers were recruited for this prospective study. Each subject received an intradermal injection of the anesthetic solution after application of the Buzzy<jats:sup>\u00ae<\/jats:sup> vibration device in one arm and another injection after ice application in the other arm. After each injection, the subjects rated pain of infiltration on a 100\u2010mm visual analog scale. Pain scores were compared using a paired <jats:italic>t<\/jats:italic> test.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twenty\u2010seven of sixty subjects (45%) reported that the 1% lidocaine\u2010epinephrine infiltration after skin cooling was more painful than after skin vibration. Eleven subjects (18.3%) gave the same pain score for both techniques. The mean pain score\u00a0\u00b1\u00a0SD was 30\u00a0\u00b1\u00a023.14 after skin cooling and 25.5\u00a0\u00b1\u00a024.1 after skin vibration. The difference between mean values was not statistically significant.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Skin vibration may be more effective than skin cooling in alleviating the pain caused by local anesthetic infiltration, although the difference was not statistically significant.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.13160","type":"journal-article","created":{"date-parts":[[2019,9,26]],"date-time":"2019-09-26T08:28:32Z","timestamp":1569486512000},"page":"1490-1493","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["A prospective comparison between skin cooling and skin vibration in reducing the pain of local anesthetic infiltration"],"prefix":"10.1111","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1694-4383","authenticated-orcid":false,"given":"Mohammed","family":"Alshahwan","sequence":"first","affiliation":[{"name":"King Saud University Riyadh Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,9,26]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2009.11.025"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1524-4725.2001.01854.x"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1308\/003588404323043382"},{"key":"e_1_2_7_5_1","first-page":"2233","volume-title":"Dermatology","author":"Hruza GJ","year":"2003"},{"key":"e_1_2_7_6_1","first-page":"83","volume-title":"Manual of Skin Surgery","author":"Leffel DJ","year":"1997"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.1996.tb00366.x"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.2165\/00148581-200507010-00004"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/01616412.1995.11740333"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/014107688107401106"},{"key":"e_1_2_7_11_1","first-page":"17","article-title":"Cryoanalgesia affords drug\u2010free anaesthesia for phaco","volume":"8","author":"Guti\u00e9rrez\u2010Carmona FJ","year":"2003","journal-title":"Eurotimes"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1080\/01676830600675392"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0099-2399(89)80094-9"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.4103\/0970-4388.160343"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2012.02522.x"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.10112"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1966.03110230098021"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1080\/01616412.1995.11740333"},{"key":"e_1_2_7_19_1","first-page":"199","article-title":"Nerve conduction velocity: relationship of skin, subcutaneous and intramuscular temperatures","volume":"61","author":"Halar EM","year":"1980","journal-title":"Arch Phys Med Rehabil"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3959(99)00099-8"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.150.3699.971"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1533-2500.2005.05203.x"},{"key":"e_1_2_7_23_1","unstructured":"CoelhoS.The importance of touch. 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