{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T01:34:25Z","timestamp":1747186465974,"version":"3.40.5"},"reference-count":14,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2019,11,29]],"date-time":"2019-11-29T00:00:00Z","timestamp":1574985600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Idiopathic calcinosis cutis is an uncommon form of calcinosis cutis. It may present as tumoral calcinosis, subepidermal calcified nodules or scrotal calcinosis. Subepidermal calcified nodules may also present as milia\u2010like lesions commonly seen in children with Down's syndrome in the absence of tissue damage or metabolic disorders, it has been seldom reported in adults. The treatment of choice is surgical excision. However, a surgical approach may not always be beneficial to the patient given the cosmetic outcomes. Here, we describe the successful use of a CO<jats:sub>2<\/jats:sub> laser in the treatment of milia\u2010like calcinosis cutis of the forehead in an adult without Down's syndrome.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>To describe the treatment of Milia\u2010like idiopathic calcinosis cutis of the forehead in an adult without Down's syndrome successfully treated with a CO<jats:sub>2<\/jats:sub> laser.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We report a case of a 48\u2010year\u2010old man who presented with skin\u2010colored hard asymptomatic papules on the forehead that started about 9 years ago, a biopsy was performed and a diagnosis of milialike calcinosis cutis was made. Surgical excision was discarded regarding the location and the number of lesions, instead, a CO<jats:sub>2<\/jats:sub> laser was used to treat this condition.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Successful laser excision of the lesions with appealing cosmetic results.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>CO<jats:sub>2<\/jats:sub> laser seems to be a valuable tool to treat milia\u2010like calcinosis cutis lesions.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.13233","type":"journal-article","created":{"date-parts":[[2019,11,29]],"date-time":"2019-11-29T12:34:12Z","timestamp":1575030852000},"page":"102-104","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Milia\u2010like idiopathic calcinosis cutis of the forehead in an adult without Down's syndrome successfully treated with a CO<sub>2<\/sub> laser"],"prefix":"10.1111","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4242-0674","authenticated-orcid":false,"given":"Miguel","family":"Aristizabal","sequence":"first","affiliation":[{"name":"Aesthetics &amp; Dermatology Institute Bogota Colombia"},{"name":"Department of Aesthetic Medicine Universidad del Rosario Bogota Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan","family":"Aristizabal","sequence":"additional","affiliation":[{"name":"Aesthetics &amp; Dermatology Institute Bogota Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela","family":"Giraldo","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital Militar Central de Colombia Bogota Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oriana","family":"Loboguerrero","sequence":"additional","affiliation":[{"name":"Department of Aesthetic Medicine Universidad del Rosario Bogota Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5183-5433","authenticated-orcid":false,"given":"Michael H.","family":"Gold","sequence":"additional","affiliation":[{"name":"Tennessee Clinical Research Center Nashville Tennessee"},{"name":"Gold Skin Care Center Nashville Tennessee"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,11,29]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"740","article-title":"A case of Down's syndrome associated with syringoma, milia, and subepidermal nodule","volume":"88","author":"Sano T","year":"1978","journal-title":"Jpn J Dermatol"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1989.01670230128029"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.3315\/jdcr.2007.1.1004"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.1996.d01-762.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2010.08.039"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2010.08.038"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ad.2015.09.001"},{"key":"e_1_2_6_9_1","doi-asserted-by":"crossref","first-page":"151","DOI":"10.2340\/0001555580152","article-title":"Solitary milia like idiopathic calcinosis cutis unassociated with Down's syndrome: two case reports","volume":"80","author":"Kim DH","year":"2000","journal-title":"Acta Dermatol Venereol"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.1981.tb01005.x"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.1996.tb03968.x"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2011.04937.x"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0039-1688846"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.3109\/14764170903356465"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/pde.13742"}],"container-title":["Journal of Cosmetic Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjocd.13233","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.13233","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jocd.13233","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.13233","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,4]],"date-time":"2023-09-04T08:54:31Z","timestamp":1693817671000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jocd.13233"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11,29]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,1]]}},"alternative-id":["10.1111\/jocd.13233"],"URL":"https:\/\/doi.org\/10.1111\/jocd.13233","archive":["Portico"],"relation":{},"ISSN":["1473-2130","1473-2165"],"issn-type":[{"type":"print","value":"1473-2130"},{"type":"electronic","value":"1473-2165"}],"subject":[],"published":{"date-parts":[[2019,11,29]]},"assertion":[{"value":"2019-09-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-11-12","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-11-29","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}