{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T04:33:39Z","timestamp":1788150819134,"version":"build-2803163510"},"reference-count":23,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2019,12,30]],"date-time":"2019-12-30T00:00:00Z","timestamp":1577664000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2020,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Cosmetic surgery and esthetic procedures have become a billion dollar industry owing to the ever\u2010growing demand of the population to stay young. The injectable treatments including fillers and botulinum toxin have become highly popular because of their quick, predictable and lasting results in the management of facial wrinkles and rejuvenation. Although these treatment modalities are relatively safe, they are associated with certain side effects.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>In this review, we will focus on the complications of fillers and botulinum toxin.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients\/Methods<\/jats:title>\n                    <jats:p>The literature research considered published journal articles (clinical trials or scientific reviews). Studies were identified by searching electronic databases (MEDLINE and PubMed) and reference lists of respective articles. Only articles available in English were considered for this review.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Brow ptosis and asymmetry are common adverse effects of botulinum toxin while the most common adverse effects associated with fillers are the local injection related effects manifesting as erythema, edema, pain, and ecchymosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>It is important that the treating physician is well verse with the various fillers and botulinum toxin complications and their management as some of the complications can be severely debilitating.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jocd.13266","type":"journal-article","created":{"date-parts":[[2019,12,31]],"date-time":"2019-12-31T00:44:36Z","timestamp":1577753076000},"page":"570-573","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":73,"title":["Complications of botulinum toxin and fillers: A narrative review"],"prefix":"10.1111","volume":"19","author":[{"given":"Martin","family":"Kassir","sequence":"first","affiliation":[{"name":"Worldwide laser institute Dallas TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mrinal","family":"Gupta","sequence":"additional","affiliation":[{"name":"Treatwell Skin Centre Jammu India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8223-2769","authenticated-orcid":false,"given":"Hassan","family":"Galadari","sequence":"additional","affiliation":[{"name":"College of Medicine and Health Sciences United Arab Emirates University Al Ain United Arab Emirates"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George","family":"Kroumpouzos","sequence":"additional","affiliation":[{"name":"Department of Dermatology Alpert Medical School of Brown University Providence Rhode Island"},{"name":"Department of Dermatology Medical School of Jundia\u00ed S\u00e3o Paulo Brazil"},{"name":"GK Dermatology, PC South Weymouth Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Katsambas","sequence":"additional","affiliation":[{"name":"University of Athens Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Torello","family":"Lotti","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of Studies Guglielmo Marconi Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aleksandra","family":"Vojvodic","sequence":"additional","affiliation":[{"name":"Military Medical Academy of Belgrade Belgrade Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephan","family":"Grabbe","sequence":"additional","affiliation":[{"name":"Department of Dermatology University Medical Center of the Johannes Gutenberg University Mainz Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Juchems","sequence":"additional","affiliation":[{"name":"Department of Dermatology University Medical Center Mainz Mainz Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8646-1179","authenticated-orcid":false,"given":"Mohamad","family":"Goldust","sequence":"additional","affiliation":[{"name":"Department of Dermatology University Medical Center Mainz Mainz Germany"},{"name":"University of Rome G. 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