{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T02:22:23Z","timestamp":1779243743402,"version":"3.51.4"},"reference-count":21,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2020,1,11]],"date-time":"2020-01-11T00:00:00Z","timestamp":1578700800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Many therapeutic modalities were reported for the treatment of warts; however, no single treatment is completely effective.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the efficacy of intralesional injection of MMR vaccine vs vitamin D in treatment of warts.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients and Methods<\/jats:title><jats:p>A total of 60 patients were included in the study divided into two groups. Group A received intralesional MMR vaccine into largest wart, and group B received intralesional vitamin D<jats:sub>3<\/jats:sub> into each lesion with maximum of five warts treated in one session. A maximum of six sessions was done every 3\u00a0weeks in both groups. Follow\u2010up was done for 6\u00a0months for any recurrence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In group A: complete response in 80%, partial response in 6.67%, minimal response in 6.67%, and no response in 6.67% of patients. About 60% of patients with multiple warts showed complete clearance of distant untreated warts. In group B: complete response in 66.7%, partial response in 6.67%, minimal response in 20%, and no response in 6.67% of patients. There was no significant difference between both groups. No recurrence was observed in both groups in the follow\u2010up period.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Immunotherapy by both intralesional MMR vaccine and vitamin D<jats:sub>3<\/jats:sub> is simple, well\u2010tolerated, effective, and cost\u2010benefit modalities for the treatment of warts.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.13272","type":"journal-article","created":{"date-parts":[[2020,1,11]],"date-time":"2020-01-11T08:52:17Z","timestamp":1578732737000},"page":"2033-2040","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Comparative clinical study of the efficacy of intralesional MMR vaccine vs intralesional vitamin D injection in treatment of warts"],"prefix":"10.1111","volume":"19","author":[{"given":"Dalia R.","family":"Shaldoum","sequence":"first","affiliation":[{"name":"MBBCh. Faculty of medicine Tanta University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9131-0263","authenticated-orcid":false,"given":"Ghada F. R.","family":"Hassan","sequence":"additional","affiliation":[{"name":"Dermatology and Venereology Faculty of medicine Tanta University Tanta Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eman H.","family":"El Maadawy","sequence":"additional","affiliation":[{"name":"Dermatology and Venereology Faculty of medicine Tanta University Tanta Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gamal M.","family":"El\u2010Maghraby","sequence":"additional","affiliation":[{"name":"Pharmaceutical Technology Faculty of pharmacy Tanta University Tanta Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,1,11]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2001.04066.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.5021\/ad.2011.23.3.282"},{"issue":"4","key":"e_1_2_6_4_1","first-page":"647","article-title":"Cutaneous warts: an evidence\u2010based approach to therapy","volume":"72","author":"Bacelieri R","year":"2005","journal-title":"Am Fam Physician"},{"issue":"1","key":"e_1_2_6_5_1","first-page":"14","article-title":"Application of cantharidin, podophyllotoxin, and salicylic acid in recalcitrant plantar warts. 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