{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T19:48:56Z","timestamp":1783712936102,"version":"3.55.0"},"reference-count":25,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2019,12,30]],"date-time":"2019-12-30T00:00:00Z","timestamp":1577664000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Several topical and systemic therapies are available for the treatment of acne vulgaris but are associated with several limitations, and recently, intense pulse light (IPL) and long\u2010pulsed 1064\u00a0nm Nd: YAG laser have shown efficacy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>The current study aimed to compare the efficacy of Nd:YAG laser and IPL in inflammatory and noninflammatory acne lesions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients and Methods<\/jats:title><jats:p>Thirty patients with inflammatory and noninflammatory facial acne were assigned randomly and equally into two groups, the Nd:YAG and IPL groups. The patients received three sessions of laser 2\u00a0weeks apart, and the clinical improvement was assessed by the reduction in the number of lesions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>At baseline, the two groups showed a nonsignificant difference as regards total number (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.476), inflammatory (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.457), and noninflammatory lesions (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.420). The improvement in total lesions was significant in the Nd:YAG Group but nonsignificant in the IPL Group (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.001, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.13, respectively). Three patients (20%) in the IPL Group showed exacerbation after the first and second sessions. One month after the last session, the difference in improvement between noninflammatory and inflammatory lesions showed a significant difference in the Nd:YAG Group (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.017) and a nonsignificant difference in the IPL Group (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.823). Nd:YAG, compared to the IPL Group, showed a significant difference as regards the improvement score in noninflammatory lesions (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.0099) and a nonsignificant difference in inflammatory lesions (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.4295).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The significant improvement in noninflammatory lesions and the absence of a significant flare\u2010up of acne as seen among patients treated with IPL make Nd:YAG a better therapeutic modality for acne.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.13278","type":"journal-article","created":{"date-parts":[[2019,12,31]],"date-time":"2019-12-31T06:02:57Z","timestamp":1577772177000},"page":"2325-2332","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Nd:YAG laser vs IPL in inflammatory and noninflammatory acne lesion treatment"],"prefix":"10.1111","volume":"19","author":[{"given":"Khaled Mohey El\u2010Din","family":"Monib","sequence":"first","affiliation":[{"name":"Department of Dermatology and Andrology Faculty of Medicine Benha University Benha Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4066-5790","authenticated-orcid":false,"given":"Mohamed Saber","family":"Hussein","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Andrology Faculty of Medicine Benha University Benha Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,12,30]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s007950100002"},{"key":"e_1_2_8_3_1","first-page":"596","article-title":"Evaluation of self\u2010treatment of mild\u2010to\u2010moderate facial acne with a blue light treatment system","volume":"10","author":"Wheeland 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