{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T16:44:52Z","timestamp":1793119492887,"version":"4.5.0"},"reference-count":25,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Actinic keratosis (AK) is a common skin disorder that is treated with different treatment modalities.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>The aim of this study was to assess the therapeutic effect of a 1540\u2010nm nonablative fractional laser on the AK.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Ten patients with 31 AK were included in the study according to the inclusion and exclusion criteria. Treatment with nonablative fractional laser (1540\u00a0nm) 3 times at 4\u00a0weeks intervals in a noncontact mode was applied. Clinical severity was assessed at each session and 3\u00a0months after the last session. It is pertinent to mention that the patients were also involved in the assessment of improvement.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The results of present study showed that in comparison to the baseline, 3\u2010session AK therapy with nonablative fractional laser significantly not only improved the AK severity by 79%, but also reduced the AK counts (from 31 to 17). On the other hand, the patients consented to the therapeutic effect.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>According to the obtained results and available studies, it seems that therapy with a 1540\u2010nm nonablative fractional laser could be considered as a safe and effective alternative therapeutic option for the treatment of AK.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.13350","type":"journal-article","created":{"date-parts":[[2020,3,2]],"date-time":"2020-03-02T07:15:41Z","timestamp":1583133341000},"page":"2893-2897","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Nonablative fractional laser therapy for treatment of actinic keratosis with 3\u2010months follow\u2010up"],"prefix":"10.1111","volume":"19","author":[{"given":"Pedram","family":"Nourmohammad Pour","sequence":"first","affiliation":[{"name":"Department of Dermatology Razi Hospital Tehran University of Medical 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