{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T16:41:06Z","timestamp":1790959266403,"version":"4.1.0"},"reference-count":5,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2020,4,6]],"date-time":"2020-04-06T00:00:00Z","timestamp":1586131200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2020,9]]},"abstract":"Abstract<\/jats:title>Background<\/jats:title>Many companies capitalized on treatable skin conditions by providing expensive prescription medications or high\u2010end over\u2010the\u2010counter cosmetics. However, patients have become more apprehensive toward these medications in lieu of their often\u2010detrimental side effect profile and reactivity with sensitive skin.<\/jats:p><\/jats:sec>Aims<\/jats:title>We developed a serum was created to counteract this budding problem. Our goal was to bring an alternative prescription acne medication that was superior in controlling acne when compared to several OTC and prescription\u2010strength medications. We created a new formulary comprising primarily of all natural glycolic acid and salicylic acid.<\/jats:p><\/jats:sec>Patients\/Methods<\/jats:title>We designed a prospective study to assess the efficacy of our serum composed of glycolic and salicylic acid for patients suffering from mild to moderate inflammatory and cystic acne, rosacea, folliculitis, and keratosis pilaris. Sixty\u2010six patients were selected ranging in age from 17 to 46. They were asked to apply the wake\u2010up serum at night for 2 weeks. At the follow\u2010up appointment, the patients were asked to fill out a questionnaire regarding the changes they have noticed with their skin.<\/jats:p><\/jats:sec>Results<\/jats:title>Over 90% of the patients reported they had significant overall improvement in acne with decrease in comedonal and cystic acne. 70%\u201080% of the patients stated decrease in oiliness, even texture, and smoother looking skin. Physical examination findings were consistent with patient\u2010reported assessment.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>A glycolic and salicylic acid combination serum may be considered an alternative treatment method for patients who wish to opt out of the typical prescription medication treatment.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.13387","type":"journal-article","created":{"date-parts":[[2020,4,6]],"date-time":"2020-04-06T13:20:11Z","timestamp":1586179211000},"page":"2349-2351","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Two is better than one: The combined effects of glycolic acid and salicylic acid on acne\u2010related disorders"],"prefix":"10.1111","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6657-976X","authenticated-orcid":false,"given":"David","family":"Wiegmann","sequence":"first","affiliation":[{"name":"William Beaumont Hospital\u2010Royal Oak Royal Oak MI"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lori","family":"Haddad","sequence":"additional","affiliation":[{"name":"William Beaumont Hospital\u2010Royal Oak Royal Oak MI"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,4,6]]},"reference":[{"key":"e_1_2_7_2_1","unstructured":"LandisM.Keratosis pilaris. Uptodate. Uptodate 22 Feb. 2016. Web. 26 Jan. 2017."},{"key":"e_1_2_7_3_1","unstructured":"GoldsteinB.Melasma. Uptodate. Uptodate 1 Mar. 2016. Web. 26 Jan. 2017."},{"key":"e_1_2_7_4_1","unstructured":"DhalM.Rosacea: pathogenesis clinical features and diagnosis. Uptodate. Uptodate 23 Jan. 2017. Web. 26 Jan. 2017."},{"key":"e_1_2_7_5_1","unstructured":"ThiboutotD.Pathogenesis clinical manifestations and diagnosis of acne vulgaris. Uptodate. Uptodate 26 Aug. 2016. Web. 26 Jan. 2017."},{"key":"e_1_2_7_6_1","unstructured":"SaidN.Postinflammatory hyperpigmentation. Uptodate. Uptodate 17 Nov. 2016. Web. 26 Jan. 2017."}],"container-title":["Journal of Cosmetic Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjocd.13387","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.13387","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jocd.13387","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.13387","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,5]],"date-time":"2023-09-05T14:57:32Z","timestamp":1693925852000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jocd.13387"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4,6]]},"references-count":5,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2020,9]]}},"alternative-id":["10.1111\/jocd.13387"],"URL":"https:\/\/doi.org\/10.1111\/jocd.13387","archive":["Portico"],"relation":{},"ISSN":["1473-2130","1473-2165"],"issn-type":[{"value":"1473-2130","type":"print"},{"value":"1473-2165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,4,6]]},"assertion":[{"value":"2019-09-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-03-05","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-04-06","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}