{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T01:34:49Z","timestamp":1747186489305,"version":"3.40.5"},"reference-count":8,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2020,5,2]],"date-time":"2020-05-02T00:00:00Z","timestamp":1588377600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"2018 Futian District Public Health Research Project","award":["FTWS2018007"],"award-info":[{"award-number":["FTWS2018007"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Pemphigus vegetans is an autoimmune bullous disorder characterized by vegetating lesions commonly over the flexures. This disorder is characterized by vegetating lesions more commonly over flexures. Cerebriform tongue, a morphology with typical pattern of sulci and gyri over dorsum of the tongue, is a well\u2010known sign seen in pemphigus vegetans.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>To emphasize the exceptional but successful use of corticosteroid and 640\u00a0nm high\u2010fluence visible red light in pemphigus vegetans.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The patient was successfully treated with low dose systemic corticosteroid (methylprednisolone 20\u00a0mg daily) and high\u2010fluence 640\u00a0nm LED red light on pustules and exudates (LIFOTRONICR, 120\u00a0mw\/cm<jats:sup>2<\/jats:sup> power density and 210\u00a0J\/cm<jats:sup>2<\/jats:sup> energy density).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The cerebriform plaques improved quickly after the treatment of corticosteroid and 640 nm high\u2010fluence visible red light.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>We propose to consider low dosage of methylprednisolone and 640\u00a0nm high fluence visible red light as first\u2010line monotherapy in pemphigus vegetans, especially in elderly patients with comorbidities and contraindications to standard therapy, as it avoids the toxicities of systemic corticosteroids and immunosuppressants.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.13420","type":"journal-article","created":{"date-parts":[[2020,5,2]],"date-time":"2020-05-02T11:49:05Z","timestamp":1588420145000},"page":"3234-3237","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Is 640\u00a0nm high\u2010fluence visible red light a valuable adjunct for treating pemphigus vegetans? A single case report"],"prefix":"10.1111","volume":"19","author":[{"given":"Jing","family":"Wang","sequence":"first","affiliation":[{"name":"Departments of Dermatology The Eighth Affiliated Hospital Sun Yat\u2010sen University Shenzhen China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoyue","family":"Wang","sequence":"additional","affiliation":[{"name":"The College of Biological Science University of California Davis, Davis CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7325-1845","authenticated-orcid":false,"given":"Yue","family":"Chen","sequence":"additional","affiliation":[{"name":"Departments of Dermatology The Eighth Affiliated Hospital Sun Yat\u2010sen University Shenzhen China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuguang","family":"Liu","sequence":"additional","affiliation":[{"name":"Departments of Pathology The Eighth Affiliated Hospital Sun Yat\u2010sen University Shenzhen China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pengfei","family":"Song","sequence":"additional","affiliation":[{"name":"Departments of Dermatology The Eighth Affiliated Hospital Sun Yat\u2010sen University Shenzhen China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,5,2]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.4103\/0019-5154.177760"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijd.IJD_152_17"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2010.03939.x"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2015.04.011"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.4103\/0378-6323.162317"},{"issue":"6","key":"e_1_2_4_7_1","first-page":"579","article-title":"Pemphigus vegetans presenting as acrodermatitis continua suppurativa","volume":"13","author":"Torok L","year":"2003","journal-title":"Eur J Dermatol"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.4314\/ajbr.v10i2.50626"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/wrr.12258"}],"container-title":["Journal of Cosmetic Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjocd.13420","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.13420","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jocd.13420","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.13420","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,4]],"date-time":"2023-09-04T05:18:17Z","timestamp":1693804697000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jocd.13420"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5,2]]},"references-count":8,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2020,12]]}},"alternative-id":["10.1111\/jocd.13420"],"URL":"https:\/\/doi.org\/10.1111\/jocd.13420","archive":["Portico"],"relation":{},"ISSN":["1473-2130","1473-2165"],"issn-type":[{"type":"print","value":"1473-2130"},{"type":"electronic","value":"1473-2165"}],"subject":[],"published":{"date-parts":[[2020,5,2]]},"assertion":[{"value":"2020-03-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-03-30","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-05-02","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}