{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:13:08Z","timestamp":1787015588415,"version":"build-2736575974"},"reference-count":26,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,5,5]],"date-time":"2020-05-05T00:00:00Z","timestamp":1588636800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Local anesthetic is one of the major ways to obtain satisfactory anesthesia in majority of plastic surgical procedures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To compare the effect on pain while injecting buffered vs nonbuffered local anesthetic.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and methods<\/jats:title>\n                    <jats:p>The single\u2010blind, split\u2010scalp study was conducted in 25 patients undergoing first hair transplant surgery after informed consent and ethics committee approval using two solutions. Solution A was composed of normal saline (200 mL), 2% lidocaine (40 mL), 1 mL of epinephrine 1:1000, and triamcinolone acetate (40 mg). Solution B was composed of normal saline (200 mL), 2% lidocaine (40 mL), 1 mL of epinephrine 1:1000, triamcinolone acetate (40 mg), and 8.4% soda bicarbonate (5 mL). A 3\u2010mL syringe with 30\u2010G needle was used. On one side of the scalp, solution A was used and solution B on the other side. The pain response was recorded using Wong\u2010Baker Faces Pain Scale corresponding to 0\u201010 scale. The data were analyzed statistically. No preoperative analgesic was used in any patient. The injections were administered by the 2nd author.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 25 patients were included in the study. The mean age of the patients was 33.4 years (range; 28 to 41 years). The average pain score was 4.96 (range, 3\u20107) with solution A whereas 3.28 (range, 2\u20106) using the solution B (P &lt; .05). Eleven of the patients (44%) were smokers. The average pain score in smokers was 5.82 with solution A and 3.73 with solution B. The pain score in nonsmokers was 4.29 with solution A and 2.93 with solution B (P &lt; .05).<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jocd.13442","type":"journal-article","created":{"date-parts":[[2020,4,18]],"date-time":"2020-04-18T15:05:33Z","timestamp":1587222333000},"page":"222-226","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Pain perception of a new Ahmad\u2010Humayun solution for local anesthesia in hair transplantation: One step ahead"],"prefix":"10.1111","volume":"20","author":[{"given":"Mohammad Humayun","family":"Mohmand","sequence":"first","affiliation":[{"name":"Plastic and Hair Restorative Surgeon Hair Transplant Institute Islamabad Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0251-688X","authenticated-orcid":false,"given":"Muhammad","family":"Ahmad","sequence":"additional","affiliation":[{"name":"Plastic and Hair Restorative Surgeon Hair Transplant Institute Islamabad Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0818-0662","authenticated-orcid":false,"given":"Mussarat","family":"Jabeen","sequence":"additional","affiliation":[{"name":"Department of Chemistry Govt Sadiq College Women University Bahawalpur Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,5,5]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.12993"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.18773\/austprescr.2011.091"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2012.05.029"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2018.04.008"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2016.09.055"},{"key":"e_1_2_5_7_1","unstructured":"KattanS KarabucakB HershEV KorostoffJM HunterP.\"Do Buffered Local Anesthetics Provide More Successful Anesthesia Over Non\u2010Buffered Solutions in Patients Requiring Dental Therapy? \u2013 A Systematic Review & Meta\u2010Analysis\".2017. Dental Theses. 19. http:\/\/repository.upenn.edu\/dental_theses\/19."},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0360-3016(92)90015-A"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2016.06.065"},{"issue":"3","key":"e_1_2_5_10_1","doi-asserted-by":"crossref","first-page":"84\u2010","DOI":"10.33589\/22.3.0084","article-title":"The efficacy of supraorbital\/supratrochlear nerve blocks in hair transplant surgery. Part II: the use of local anaesthetic cream","volume":"22","author":"Ahmad M","year":"2012","journal-title":"Hair Transpl Forum Intnl"},{"issue":"1","key":"e_1_2_5_11_1","first-page":"19","article-title":"Nerve Blocks OR Subcutaneous injections: comparison of pain levels in patients undergoing hair transplant surgery","volume":"4","author":"Ahmad M","year":"2015","journal-title":"Pak J Plast Surg"},{"issue":"4","key":"e_1_2_5_12_1","first-page":"555595","article-title":"Supraorbital\/supratrochlear nerve blocks: clinical significance of the superior and anterior approaches","volume":"2","author":"Ahmad M","year":"2017","journal-title":"J Anaesthesia Intensive Care Med"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.29328\/journal.adr.1001001"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/DSS.0000000000001304"},{"key":"e_1_2_5_15_1","unstructured":"Wong Baker Faces Pain Scale.www.wongbakerfaces.org. Accessed on 01\u201301\u20102020."},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/727630"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.2344\/0003-3006-57.2.59"},{"key":"e_1_2_5_18_1","first-page":"74","article-title":"Effect of a new local anesthetic buffering device on pain reduction during nerve block injections","volume":"63","author":"Comerci AW","year":"2015","journal-title":"Gen Dent"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1177\/229255031302100413"},{"issue":"1","key":"e_1_2_5_20_1","first-page":"25","article-title":"Double\u2010blind crossover study to compare pain experience during inferior alveolar nerve block administration using buffered two percent lidocaine in children","volume":"38","author":"Chopra R","year":"2016","journal-title":"Pediatr Dent"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1177\/229255031202000207"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(03)00644-7"},{"issue":"6","key":"e_1_2_5_23_1","first-page":"643","article-title":"Effect of warm lidocaine on the sensory onset of epidural anesthesia: a randomized trial","volume":"32","author":"Liu FC","year":"2009","journal-title":"Chang Gung Med J"},{"key":"e_1_2_5_24_1","unstructured":"RassmanWR.Personal communication 2018 annual conference of FUE Europe Manchester UK."},{"key":"e_1_2_5_25_1","first-page":"19","volume-title":"Step by Step Hair Transplantation","author":"Kumar A","year":"2019"},{"issue":"5","key":"e_1_2_5_26_1","doi-asserted-by":"crossref","first-page":"149","DOI":"10.33589\/15.5.0149","article-title":"Hair Transplantation without Post\u2010operative Edema","volume":"15","author":"Abbasi G","year":"2005","journal-title":"Hair Transpl Forum Intnl"},{"key":"e_1_2_5_27_1","doi-asserted-by":"publisher","DOI":"10.1177\/074880688700400403"}],"container-title":["Journal of Cosmetic Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjocd.13442","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.13442","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jocd.13442","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.13442","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,3]],"date-time":"2023-09-03T06:57:45Z","timestamp":1693724265000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jocd.13442"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5,5]]},"references-count":26,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["10.1111\/jocd.13442"],"URL":"https:\/\/doi.org\/10.1111\/jocd.13442","archive":["Portico"],"relation":{},"ISSN":["1473-2130","1473-2165"],"issn-type":[{"value":"1473-2130","type":"print"},{"value":"1473-2165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,5,5]]},"assertion":[{"value":"2020-03-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-04-13","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-05-05","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}