{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T01:32:36Z","timestamp":1747186356950,"version":"3.40.5"},"reference-count":25,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,7,21]],"date-time":"2020-07-21T00:00:00Z","timestamp":1595289600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Laser treatment has emerged as a novel treatment modality for onychodystrophy. Only a few small series have assessed the efficacy of laser treatment in onychodystrophy, most of which were case reports. The therapeutic effect of the 1064\u00a0nm neodymium\u2010doped:yttrium aluminum garnet (Nd:YAG) laser for onychodystrophy has been demonstrated. Recently, the picosecond Nd:YAG (PSNY) laser has been introduced to improve various skin disorders.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>The aim of this study was to verify the efficacy of a 1064\u00a0nm PSNY in management of idiopathic onychodystrophy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We present a case series of dystrophic nails treated with a PSNY for onychodystrophy improvement. Planimetry using ImageJ software was used to calculate lesion reduction and proximal clear nail growth. Clinical improvement was assessed using a 5\u2010point Global Assessment Scale (GAS). Adverse events were also assessed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twenty\u2010five patients (11 males and 14 females) with a total of 128 nails (94 finger nails and 34 toe nails) were treated. The mean treatment number was 8.7\u00a0\u00b1\u00a06.2, and the mean total duration of treatment was 33.4\u00a0\u00b1\u00a034.6\u00a0weeks. The average proportion of the lesion area decreased significantly (from 65.9% to 46.6%) after PSNY treatment (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.001). The mean GAS (3.16\u00a0\u00b1\u00a01.18) exhibited fair improvement, and there were no serious adverse events.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The 1064\u00a0nm PSNY laser can provide fair improvement for onychodystrophy with a good prognosis at least during the follow\u2010up period and optimal cosmetic results in Asian patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.13580","type":"journal-article","created":{"date-parts":[[2020,6,27]],"date-time":"2020-06-27T21:50:45Z","timestamp":1593294645000},"page":"497-505","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Treatment of idiopathic onychodystrophy with a 1064 nm picosecond neodymium\u2010doped:yttrium aluminum garnet laser: A retrospective study"],"prefix":"10.1111","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7677-7308","authenticated-orcid":false,"given":"Yun Ho","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Dermatology Kangbuk Samsung Hospital Sungkyunkwan University School of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heun Joo","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Dermatology Kangbuk Samsung Hospital Sungkyunkwan University School of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Won\u2010Serk","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Dermatology Kangbuk Samsung Hospital Sungkyunkwan University School of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ga\u2010Young","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Dermatology Kangbuk Samsung Hospital Sungkyunkwan University School of Medicine Seoul 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