{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T01:46:34Z","timestamp":1777686394688,"version":"3.51.4"},"reference-count":29,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T00:00:00Z","timestamp":1596240000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Cleft lip is a congenital development defect. Primary cleft lip repair leads to cleft scar formation. The resulting scar often undergoes hypertrophy, which negatively affects the facial esthetics, function, and patient's mental health. One of the methods used in scar therapy described in recent years is botulinum toxin injections The aim of this work is to present current knowledge about the impact of botulinum toxin A on cleft lip scar appearance and its effect on scar hypertrophy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The literature search was conducted in the English language via the PubMed and Google Scholar databases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The results show injections seem to be a promising method in cleft lip scar management. However, future studies, especially randomized controlled trials, are necessary to assess the effect of BoNT\u2010A compared with placebo and to determine the optimal dosages and injection schemes for BoNT\u2010A treatment in cleft lip patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.13614","type":"journal-article","created":{"date-parts":[[2020,7,12]],"date-time":"2020-07-12T12:09:28Z","timestamp":1594555768000},"page":"2188-2193","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Botulinum toxin type A as a novel method of preventing cleft lip scar hypertrophy\u2014A literature review"],"prefix":"10.1111","volume":"19","author":[{"given":"Patrycja","family":"Bartkowska","sequence":"first","affiliation":[{"name":"Students Scientific Society of Maxillofacial Orthopaedics and Orthodontics University of Medical Sciences Pozna\u0144 Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Justyna","family":"Roszak","sequence":"additional","affiliation":[{"name":"Students Scientific Society of Maxillofacial Orthopaedics and Orthodontics University of Medical Sciences Pozna\u0144 Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hubert","family":"Ostrowski","sequence":"additional","affiliation":[{"name":"Students Scientific Society of Maxillofacial Orthopaedics and Orthodontics University of Medical Sciences Pozna\u0144 Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1037-3711","authenticated-orcid":false,"given":"Oskar","family":"Komisarek","sequence":"additional","affiliation":[{"name":"Department of Maxillofacial Orthopaedics and Orthodontics Poznan University of Medical Sciences Pozna\u0144 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