{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T02:44:16Z","timestamp":1789699456204,"version":"4.0.1"},"reference-count":13,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,8,30]],"date-time":"2020-08-30T00:00:00Z","timestamp":1598745600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Recipient site necrosis is a rare but potentially devastating complication of hair restoration surgery. Appropriate case selection and procedure performed by expert surgical team are although mandatory but not enough to prevent such event, particularly in megasessions. Timely recognition of impending necrosis is very important to consider preventive measures.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>We aim to evaluate the use of topical nitroglycerine in preventing the incidence of impending necrosis in hair restoration surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective observational study was designed to determine the efficacy of nitroglycerine spray in consecutive cases of hair transplant troubled with dusky skin vulnerable to necrosis. 1580 cases that underwent hair transplant were enrolled and topical nitroglycerine was used in 88 patients vulnerable to necrosis. A management algorithm was also proposed from clinical observations and literature review to avoid vascular injury that may lead to necrosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>83 cases (94.32%) were rescued by topical nitroglycerine and five developed necrosis eventually. Five cases who had considerable black hue and treated successfully with above treatment were reported in detail.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our experience with the use of nitroglycerine spray on the cyanotic area aided in the prevention of impending necrosis due to its vasodilatory effects on arterioles.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.13659","type":"journal-article","created":{"date-parts":[[2020,8,5]],"date-time":"2020-08-05T21:15:04Z","timestamp":1596662104000},"page":"906-910","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Prevention of impending scalp necrosis by topical nitroglycerine in hair transplant surgery"],"prefix":"10.1111","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6791-0218","authenticated-orcid":false,"given":"Zaheer","family":"Abbas","sequence":"first","affiliation":[{"name":"Hormozgan University of Medical Sciences Bandarabbas Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamid","family":"Kufi","sequence":"additional","affiliation":[{"name":"Hormozgan University of Medical Sciences Bandarabbas Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,8,30]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12721603"},{"issue":"3","key":"e_1_2_8_3_1","first-page":"41","article-title":"Feily\u2019s method as new mode of hair grafting in prevention of scalp necrosis even in dense hair transplantation","volume":"5","year":"2015","journal-title":"Dermatol Pract Concept"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/archfaci.1.1.27"},{"key":"e_1_2_8_5_1","first-page":"119","article-title":"Is transdermal nitroglycerin application effective in preventing and healing flap ischaemia after modified radical mastectomy?","volume":"48","author":"Kutun S","year":"2010","journal-title":"S Afr J Surg"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2013.12.040"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/dsu.12001"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/asj\/sjv018"},{"issue":"9","key":"e_1_2_8_9_1","first-page":"37","article-title":"Vascular compromise from soft tissue augmentation: experience with 12 cases and recommendations for optimal outcomes","volume":"7","author":"Beleznay K","year":"2014","journal-title":"J Clin Aesthet Dermatol"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.5999\/aps.2017.00934"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.asj.2008.11.005"},{"key":"e_1_2_8_12_1","first-page":"806","volume-title":"The pharmacological basis for therapeutics","author":"Needleman P","year":"1985"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI110093"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2008.34249.x"}],"container-title":["Journal of Cosmetic Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjocd.13659","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.13659","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jocd.13659","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.13659","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,30]],"date-time":"2023-08-30T03:46:51Z","timestamp":1693367211000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jocd.13659"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,30]]},"references-count":13,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,3]]}},"alternative-id":["10.1111\/jocd.13659"],"URL":"https:\/\/doi.org\/10.1111\/jocd.13659","archive":["Portico"],"relation":{},"ISSN":["1473-2130","1473-2165"],"issn-type":[{"value":"1473-2130","type":"print"},{"value":"1473-2165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8,30]]},"assertion":[{"value":"2020-06-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-07-30","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-08-30","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}