{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T16:24:41Z","timestamp":1790699081025,"version":"4.1.0"},"reference-count":25,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2020,11,23]],"date-time":"2020-11-23T00:00:00Z","timestamp":1606089600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100009570","name":"Srinakharinwirot University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009570","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The popularity of laser therapy in acne treatment has been increasing recently due to its safety, effectiveness, and convenience. Both 595\u2010nm pulsed dye laser (PDL) and 1064\u2010nm long\u2010pulsed neodymium:yttrium\u2010aluminum\u2010garnet laser (Nd:YAG) have been successful in treating inflammatory acne lesions. However, clinical data from controlled comparative studies are still lacking.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>To compare the clinical efficacy of 1064\u2010nm Nd:YAG with 595\u2010nm PDL for the treatment of acne vulgaris.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Thirty\u2010four participants with mild to moderate facial acne were enrolled and then randomized to receive three, 2\u2010week interval treatments with 1064\u2010nm Nd:YAG on one side of the face and 595\u2010nm PDL on the other side. Clinical assessments including acne lesion counts, acne erythema grading, and erythema index were performed at baseline, 2nd, 4th, and 8th week. Participants\u2019 satisfaction, preference, and adverse effects were recorded.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>As compared with baseline, the significant reduction of mean inflammatory acne lesion counts, acne erythema grading, and erythema index was demonstrated on 595\u2010nm PDL\u2010treated sides and 1064\u2010nm Nd:YAG\u2010treated sides. However, there were no significant differences between both sides. The participants were satisfied with both laser treatments, but the participants preferred 1064\u2010nm Nd:YAG over 595\u2010nm PDL treatment. The adverse effects were less on 1064\u00a0nm Nd: YAG\u2010treated sides.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>1064\u2010nm Nd:YAG and 595\u2010nm PDL treatments are equally effective in reducing inflammatory acne lesions and acne erythema in mild to moderate facial acne vulgaris.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.13832","type":"journal-article","created":{"date-parts":[[2020,11,24]],"date-time":"2020-11-24T03:54:50Z","timestamp":1606190090000},"page":"2108-2115","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":34,"title":["The comparative study of efficacy between 1064\u2010nm long\u2010pulsed Nd:YAG laser and 595\u2010nm pulsed dye laser for the treatment of acne vulgaris"],"prefix":"10.1111","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5771-5336","authenticated-orcid":false,"given":"Napith","family":"Chalermsuwiwattanakan","sequence":"first","affiliation":[{"name":"Skin Center Faculty of Medicine Srinakharinwirot University Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salinee","family":"Rojhirunsakool","sequence":"additional","affiliation":[{"name":"Skin Center Faculty of Medicine Srinakharinwirot University Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nanticha","family":"Kamanamool","sequence":"additional","affiliation":[{"name":"Department of Preventive and Social Medicine Faculty of Medicine Srinakharinwirot University Bangkok 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Pulsed light Versus 1,064 Long\u2010Pulsed Neodymium: Yttrium\u2010Aluminum\u2010 Garnet Laser in the Treatment of Facial Acne Vulgaris","volume":"10","author":"Mohamed EE","year":"2016","journal-title":"J Clin Diagn Res"},{"key":"e_1_2_9_18_1","first-page":"2","article-title":"Treatment of Acne Vulgaris with 1064 nm Nd:YAG Laser","volume":"15","author":"Ruta Ganceviciene RM","year":"2015","journal-title":"J Laser Health Acad"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.13278"},{"issue":"11","key":"e_1_2_9_20_1","first-page":"1025","article-title":"The use of the low\u2010fluence 1064 nm Nd:YAG laser in a female with contraindications to systemic anti\u2010acne therapy","volume":"8","author":"Ballin JS","year":"2009","journal-title":"J Drugs 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