{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T16:59:10Z","timestamp":1788886750951,"version":"build-2803163510"},"reference-count":39,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,12,25]],"date-time":"2020-12-25T00:00:00Z","timestamp":1608854400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Acne scars carry a huge physical and psychological impact on people. This article aims to evaluate the role of fractional radiotherapy in treatment of atrophic acne scars. The main objective includes providing an up\u2010to\u2010date review of existing literature, presenting the most significant studies conducted in this field.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In order to study the impact of fractional radiotherapy on the appearance of atrophic acne scars, we conducted a search on Pubmed using the keywords \u201cfractional radiotherapy\u201d, combined with\/or \u201cacne\u201d, \u201catrophic acne scars\u201d and \u201cacne scars\u201d and found 75 papers, from which we selected 39.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There are several therapeutic approaches for the improvement of acne scars with variable results and possible side effects. Fractional radiofrequency system has been used widely in the last years, as it turned out to be an effective treatment method, either in combination with other modalities, or alone.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>There are no generalized clinical guidelines adopted to standardize atrophic acne scar treatment. The multiple therapeutic options available create a dilemma in choosing the proper method in order to enhance its efficacy and to minimize its risks. The accumulated experience in nonablative collagen stimulating devices like fractional radiofrequency has proven that thickening of interstitial fibers in the dermis is possible with a controlled thermal injury, without epidermal damage and development of side effects.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.13900","type":"journal-article","created":{"date-parts":[[2020,12,24]],"date-time":"2020-12-24T14:35:05Z","timestamp":1608820505000},"page":"381-385","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Benefits of fractional radiofrequency treatment in patients with atrophic acne scars \u2010 Literature review"],"prefix":"10.1111","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3748-9634","authenticated-orcid":false,"given":"Cristina","family":"Cucu","sequence":"first","affiliation":[{"name":"Skin Laser Surgery Clinic Bucharest Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1627-6912","authenticated-orcid":false,"given":"Alexandra\u2010Irina","family":"Butacu","sequence":"additional","affiliation":[{"name":"Department of Dermatology Colentina Clinical Hospital \u201cCarol Davila\u201d University of Medicine and Pharmacy Bucharest Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bogdan\u2010Dimitrie","family":"Niculae","sequence":"additional","affiliation":[{"name":"Skin Laser Surgery Clinic Bucharest Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8719-6952","authenticated-orcid":false,"given":"George\u2010Sorin","family":"Tiplica","sequence":"additional","affiliation":[{"name":"Department of Dermatology Colentina Clinical Hospital \u201cCarol Davila\u201d University of Medicine and Pharmacy Bucharest Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,12,25]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2015.29"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s007950100002"},{"key":"e_1_2_7_4_1","unstructured":"SaediN UebelhoerN.Management of acne scars. 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