{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:14:12Z","timestamp":1787015652076,"version":"build-2736575974"},"reference-count":17,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2021,2,6]],"date-time":"2021-02-06T00:00:00Z","timestamp":1612569600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Soft tissue filler injections are frequently performed with a relatively low number of severe adverse events reported. While venous complications have been described, the majority of adverse events are generally associated with the arterial vascular system. Intra\u2010arterial product application can present with pain, skin discoloration, and potential tissue loss and\/or injection related visual compromise.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>We present the clinical case and the consecutive symptomology of a 39\u2010year\u2010old woman injected with calcium hydroxylapatite at the zygomatic arch with five perpendicular needle (27G 12mm) supraperiosteal bolus injections of 0.2\u00a0cc per site.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Immediately after the injections, weakness, nausea, vomiting, and loss of consciousness occurred. Additionally, left\u2010sided loss of sensation of her face, scalp, oral, and nasal mucosa occurred, with absence of left corneal reflex and ipsi\u2010lateral ear congestion. Subsequently, left\u2010sided masseteric atrophy and dysphagia occurred.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>One year after the injection procedure the sensory loss of her facial skin and scalp persisted, while the other symptoms improved. Medications involved in the symptomatic (not causal) partial recovery process were Dexamethasone, Vitamin B complex, Vinpocetine, Pentoxifyllin, and Thioctic acid.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The symptoms presented and the time\u2010related relationship to the injection procedure increases the likeliness of an association between the administration of the calcium hydroxylapatite product and a lesion of the trigeminal ganglion. The resulting symptoms can altogether be related to the functions of the ganglion. The connecting pathway between the injection site and the ganglion can be explained by the arterial vascular pathway.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jocd.13959","type":"journal-article","created":{"date-parts":[[2021,2,8]],"date-time":"2021-02-08T13:34:12Z","timestamp":1612791252000},"page":"1505-1511","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Acute isolated trigeminal neuropathy following calcium hydroxylapatite\u2010based soft tissue filler injection: A case report"],"prefix":"10.1111","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6164-9810","authenticated-orcid":false,"given":"Leniza","family":"Mingazova","sequence":"first","affiliation":[{"name":"Russian Department of Nervous Diseases Post\u2010Graduate Education Institute I.M.Sechenov First Moscow State Medical University (Sechenov University) Moscow Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Karpova","sequence":"additional","affiliation":[{"name":"Russian Department of Dermatological Diseases and Cosmetology Pirogov Russian National Research Medical University Moscow Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stanislav","family":"Murakov","sequence":"additional","affiliation":[{"name":"Department of Dermatovenerology and Cosmetology Academy of Postgraduate Education under FSCC of FMBA of Russia Moscow Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olga","family":"Orlova","sequence":"additional","affiliation":[{"name":"Russian Department of Nervous Diseases Post\u2010Graduate Education Institute I.M.Sechenov First Moscow State Medical University (Sechenov University) Moscow Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valery","family":"Golubev","sequence":"additional","affiliation":[{"name":"Russian Department of Nervous Diseases Post\u2010Graduate Education Institute I.M.Sechenov First Moscow State Medical University (Sechenov University) Moscow Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7210-6566","authenticated-orcid":false,"given":"Sebastian","family":"Cotofana","sequence":"additional","affiliation":[{"name":"Department of Clinical Anatomy Mayo Clinic College of Medicine and Science Rochester MN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,2,6]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0000000000005201"},{"key":"e_1_2_8_3_1","first-page":"58","article-title":"Arterial supply of the trigeminal ganglion, a micromorphological study","volume":"79","author":"\u0106etkovi\u0107 M","year":"2020","journal-title":"Folia Morphol"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e3181a20544"},{"issue":"3","key":"e_1_2_8_5_1","first-page":"e652","article-title":"The new transverse\u2013facial artery musculomucosal flap for intraoral reconstructions","volume":"4","author":"Pompei B","year":"2016","journal-title":"Plast Reconstr Surg"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4637.2011.01277.x"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2005-836601"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0000000000000537"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.62.3.297-a"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00266-012-9876-3"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/jon.12476"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004150050497"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.38.10.1529"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/0303-8467(94)90055-8"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/GOX.0000000000000128"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/dth.14183"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.5999\/aps.2020.00752"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/DSS.0000000000001683"}],"container-title":["Journal of Cosmetic Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.13959","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jocd.13959","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.13959","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T07:27:24Z","timestamp":1693553244000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jocd.13959"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,6]]},"references-count":17,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2021,5]]}},"alternative-id":["10.1111\/jocd.13959"],"URL":"https:\/\/doi.org\/10.1111\/jocd.13959","archive":["Portico"],"relation":{},"ISSN":["1473-2130","1473-2165"],"issn-type":[{"value":"1473-2130","type":"print"},{"value":"1473-2165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,2,6]]},"assertion":[{"value":"2020-08-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-11-06","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-02-06","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}