{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T22:01:15Z","timestamp":1775599275964,"version":"3.50.1"},"reference-count":32,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2021,3,14]],"date-time":"2021-03-14T00:00:00Z","timestamp":1615680000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Alopecia areata (AA) is an inflammatory condition that causes regional shedding without scarring on the hair or eyebrows, eyelashes, and beard. In studies conducted, it has been concluded that platelet\/lymphocyte ratio (PLR), neutrophil\/lymphocyte ratio (NLR), and mean platelet volume (MPV) are significant indicators of systemic inflammation in various diseases. In the present study, our aim was to examine these parameters in AA patients and to investigate their relationship with the disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>A total of 135 AA patients and 135 healthy controls who did not have any systemic, inflammatory, infectious, or autoimmune diseases were included in this study. Demographic characteristics and complete blood count (CBC) results were analyzed retrospectively and recorded, and statistical analysis was performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>PLR, NLR, and MPV values were not differ between AA patients and the control group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>It can be concluded that PLR, NLR, and MPV values are not convenient parameters to show inflammatory response in AA.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.14048","type":"journal-article","created":{"date-parts":[[2021,3,8]],"date-time":"2021-03-08T08:01:04Z","timestamp":1615190464000},"page":"4048-4051","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Investigation of the relationship between alopecia areata and inflammatory blood parameters"],"prefix":"10.1111","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3057-6871","authenticated-orcid":false,"given":"G\u00f6kt\u00fcrk","family":"Dere","sequence":"first","affiliation":[{"name":"Department of Dermatology Ordu State Hospital Ordu Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5698-8690","authenticated-orcid":false,"given":"Mustafa","family":"G\u00fcndo\u011fdu","sequence":"additional","affiliation":[{"name":"Department of Dermatology Ordu State Hospital Ordu Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,3,14]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2017.04.1141"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1087-0024.2004.00835.x"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.3109\/14397595.2015.1091136"},{"issue":"2","key":"e_1_2_9_5_1","first-page":"161","article-title":"Evaluation of neutrophil\u2010to\u2010lymphocyte ratio, platelet to\u2010lymphocyte ratio, and mean platelet volume in patients with lichen planus","volume":"26","author":"An I","year":"2019","journal-title":"Ann Med Res"},{"issue":"4","key":"e_1_2_9_6_1","first-page":"847","article-title":"Neutrophil to lymphocyte ratio is a useful predictor of atrial fibrillation in patients with diabetes mellitus","volume":"29","author":"Sahin S","year":"2013","journal-title":"Acta Medica Mediterranea"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00508-014-0683-5"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1590\/1806-9282.63.12.1065"},{"issue":"1","key":"e_1_2_9_9_1","first-page":"60","article-title":"Neutrophil to lymphocyte ratio is useful in differentiation of malign and benign thyroid nodules","volume":"38","author":"Sit M","year":"2019","journal-title":"P R Health Sci J"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.4314\/ahs.v19i1.35"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.5114\/fmpcr.2020.95311"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/9213074"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1590\/1806-9282.65.1.38"},{"issue":"3","key":"e_1_2_9_14_1","first-page":"417","article-title":"Mean platelet volume: an overlooked herald of malignant thyroid nodules","volume":"58","author":"Sit M","year":"2019","journal-title":"Acta Clin Croat"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.4149\/BLL_2021_017"},{"issue":"3","key":"e_1_2_9_16_1","first-page":"263","article-title":"Association of mean platelet volume and red blood cell distribution width with coronary collateral development in stable coronary artery disease","volume":"14","author":"Sincer I","year":"2018","journal-title":"Adv Int Cardiol\/Post\u0119py w Kardiologii Interwencyjnej"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.15562\/bmj.v7i3.806"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.7727\/wimj.2013.011"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1103442"},{"issue":"9","key":"e_1_2_9_20_1","first-page":"751","article-title":"Alopecia areata: Part 1: pathogenesis, diagnosis, and prognosis","volume":"61","author":"Spano F","year":"2015","journal-title":"Can Fam Physician"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2014.10.014"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaut.2018.12.001"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.13254"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1080\/15569527.2019.1684316"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1586\/erc.12.159"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinre.2012.06.004"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabet.2015.01.001"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000017537"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep35378"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/1346-8138.13061"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.13131"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1177\/0003319717718329"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-009-1323-8"}],"container-title":["Journal of Cosmetic Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.14048","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jocd.14048","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.14048","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,23]],"date-time":"2023-08-23T20:52:18Z","timestamp":1692823938000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jocd.14048"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,14]]},"references-count":32,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["10.1111\/jocd.14048"],"URL":"https:\/\/doi.org\/10.1111\/jocd.14048","archive":["Portico"],"relation":{},"ISSN":["1473-2130","1473-2165"],"issn-type":[{"value":"1473-2130","type":"print"},{"value":"1473-2165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,3,14]]},"assertion":[{"value":"2021-02-01","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-03-02","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-03-14","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}