{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T00:52:13Z","timestamp":1791507133919,"version":"4.3.4"},"reference-count":30,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2021,5,6]],"date-time":"2021-05-06T00:00:00Z","timestamp":1620259200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2021,5,6]],"date-time":"2021-05-06T00:00:00Z","timestamp":1620259200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Non\u2010surgical hair restoration is one of the most exciting and innovative fields in cosmetic surgery today.\u00a0The addition of latest technique like derma roller seeks to achieve better results for delivering pharmaceutical solution for hair growth in comparison with topical administration.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>\n                      We aim to compare intradermal injection vs. derma roller technique for administration of QR678Neo\n                      <jats:sup>\u00ae<\/jats:sup>\n                      hair regrowth therapy for the treatment of androgenetic alopecia (AGA) in male and female patients.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>\n                      A sum of 50 patients in the age range of 20\u201370\u00a0years with AGA were included and divided into 2 groups; Group A (intradermal) and Group B (derma roller). Intradermal injection of QR678Neo\n                      <jats:sup>\u00ae<\/jats:sup>\n                      formulation and derma roller with superficial application of QR678Neo\n                      <jats:sup>\u00ae<\/jats:sup>\n                      was given in each group. Assessment was done using hair pull test, global photographic assessment, video\u2010microscopic assessment, and patient subjective assessment at baseline, 6\u00a0months, and 1\u00a0year.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Significant diminution in hair fall was seen in both the groups. All the video\u2010microscopic assessment factors were better in intradermal injection group compared to the derma roller group, but not significant. Erythema and pain were high in derma roller group in compare to intradermal.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Derma roller technique is more convenient and easy to perform, especially when the availability of a trained person to carry out intradermal injection is not feasible, it gives satisfactory results. It is also beneficial in needle phobic and apprehensive patients. Though the results are more efficacious with intradermal scalp injection technique, this study established satisfactory results with derma roller technique as well.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jocd.14139","type":"journal-article","created":{"date-parts":[[2021,4,7]],"date-time":"2021-04-07T16:16:54Z","timestamp":1617812214000},"page":"3299-3307","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Evaluation of efficacy of intradermal injection therapy vs derma roller application for administration of QR678 Neo\n                    <sup>\u00ae<\/sup>\n                    hair regrowth formulation for the treatment of Androgenetic Alopecia\u2014A prospective study"],"prefix":"10.1111","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2163-1170","authenticated-orcid":false,"given":"Debraj","family":"Shome","sequence":"first","affiliation":[{"name":"Department of Facial Plastic Surgery &amp; Facial Cosmetic Surgery &amp; Director The Esthetic Clinics Mumbai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rinky","family":"Kapoor","sequence":"additional","affiliation":[{"name":"Department of Dermatology Cosmetic Dermatology &amp; Dermato\u2010Surgery The Esthetic Clinics Mumbai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sapna","family":"Vadera","sequence":"additional","affiliation":[{"name":"Department of Facial Plastic Surgery &amp; Facial Cosmetic Surgery The Esthetic Clinics Mumbai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Komal","family":"Doshi","sequence":"additional","affiliation":[{"name":"Department of Facial Plastic Surgery &amp; Facial Cosmetic Surgery The Esthetic Clinics Mumbai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ghanshyam","family":"Patel","sequence":"additional","affiliation":[{"name":"Veeda Clinical Research Ahmedabad India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Temoor","family":"Mohammad Khan","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery Osmania Medical College Hyderabad India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,5,6]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12512509"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.4103\/0974-7753.90799"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ad.2014.07.006"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.111570"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a013615"},{"key":"e_1_2_9_7_1","unstructured":"JonesMC.Treatment options for androgenetic alopecia. 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