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Injectable treatments like botulinum toxin are becoming more popular owing to their rapid, well\u2010defined, and lasting results for the reduction of facial fine lines, wrinkles, and facial rejuvenation. These emerging treatments are quite safe but can have certain adverse effects. In this article, we have highlighted the complications and side effects of botulinum toxin based on the anatomical location. The possible causes and precautions to prevent these complications are also discussed. The search of literature included peer\u2010reviewed articles including clinical trials and scientific reviews. Literature was identified from electronic databases (MEDLINE\/PubMed) through January 2021 and references of respective articles and only the articles published in English language were included.<\/jats:p>","DOI":"10.1111\/jocd.14160","type":"journal-article","created":{"date-parts":[[2021,4,17]],"date-time":"2021-04-17T05:17:13Z","timestamp":1618636633000},"page":"1585-1590","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":60,"title":["Complications of Botulinum toxin A: An update review"],"prefix":"10.1111","volume":"20","author":[{"given":"George","family":"Kroumpouzos","sequence":"first","affiliation":[{"name":"Department of Dermatology Alpert Medical School of Brown University Providence RI USA"},{"name":"Department of Dermatology Medical School of Jundia\u00ed S\u00e3o Paulo Brazil"},{"name":"GK Dermatology, PC South Weymouth MA 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