{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T23:58:05Z","timestamp":1789603085232,"version":"build-2803163510"},"reference-count":25,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2021,6,6]],"date-time":"2021-06-06T00:00:00Z","timestamp":1622937600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Sensitive skin is subjective cutaneous hyperreactivity to environmental factors. Demodicosis is a skin disorder caused by <jats:italic>Demodex mites<\/jats:italic>. There may be a link between demodicosis and sensitive skin.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>This study aimed to examine facial <jats:italic>Demodex mites<\/jats:italic> density and other factors associated with sensitive skin in patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and methods<\/jats:title><jats:p>A total of 349 randomly selected patients presented to the dermatology department. The research data were collected using a questionnaire form that included the participants\u2019 sociodemographic and lifestyle characteristics, a sensitive skin questionnaire, the Dermatology Life Quality Index (DLQI), and European Health Interview Survey (EHIS). Patients underwent standardized superficial skin surface biopsy of 4 areas of the face. <jats:italic>D<\/jats:italic>.\u00a0<jats:italic>folliculorum<\/jats:italic> count greater than 5\u00a0mites\/cm<jats:sup>2<\/jats:sup> was considered positive.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In relation to <jats:italic>Demodex<\/jats:italic>, there was an increase in skin sensitivity with higher <jats:italic>Demodex<\/jats:italic> density (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.04). There was a statistically significant, weak positive correlation between skin sensitivity and DLQI score (r\u00a0=\u00a00.33, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.00), and there was also a significant but very weak negative correlation between skin sensitivity and EUROHIS (r\u00a0=\u00a0\u22120.164, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.002). Skin sensitivity was more common in patients with a concomitant dermatological disease (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.01) and increased with more frequent cosmetic use (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.00).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Alongside other risk factors, for the patients presenting with complaints of sensitive skin, investigating Demodex population density may help alleviate sensitive skin symptoms with appropriate therapies and preventive measures.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.14246","type":"journal-article","created":{"date-parts":[[2021,5,22]],"date-time":"2021-05-22T13:40:38Z","timestamp":1621690838000},"page":"1610-1615","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Demodex infestation as a cause of sensitive skin in a dermatology outpatient 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