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Psoriasis exacerbation could be interconnected with epidermal or mucosal colonization with streptococci, <jats:italic>Malassezia<\/jats:italic>, <jats:italic>Staphylococcus aureus<\/jats:italic>, or <jats:italic>Candida albicans<\/jats:italic>. The role of cutaneous and gut microbiome in psoriasis pathogenesis has recently been studied in both human and animal models. In this review, we try to evaluate various pathogenic mechanisms linking the microbiota and psoriasis. The literature research included peer\u2010reviewed articles which included clinical trials, original reports, and scientific reviews. MEDLINE and PubMed databases were searched from January 1990 to March 2021, including the reference lists of articles meeting our criteria.<\/jats:p>","DOI":"10.1111\/jocd.14273","type":"journal-article","created":{"date-parts":[[2021,6,5]],"date-time":"2021-06-05T07:40:21Z","timestamp":1622878821000},"page":"1402-1406","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Psoriasis: Embarking a dynamic shift in the skin microbiota"],"prefix":"10.1111","volume":"21","author":[{"given":"Mrinal","family":"Gupta","sequence":"first","affiliation":[{"name":"DNB Dermatology Consultant Dermatologist Treatwell Skin Centre  Jammu India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey M.","family":"Weinberg","sequence":"additional","affiliation":[{"name":"Icahn School of Medicine at Mount Sinai  New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul 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