{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T18:19:05Z","timestamp":1788200345228,"version":"build-2803163510"},"reference-count":21,"publisher":"Wiley","issue":"S2","license":[{"start":{"date-parts":[[2021,7,28]],"date-time":"2021-07-28T00:00:00Z","timestamp":1627430400000},"content-version":"vor","delay-in-days":27,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Acne vulgaris is a common skin condition affecting the pilosebaceous unit of the skin characterized by the presence of comedones, papules, pustules, nodules, and cysts, which might result in permanent scars. It commonly affects adolescents, but it can occur in any age\u2010group with the second group of incidence in young women in their 30s.<\/jats:p><jats:p>Acne vulgaris can highly affect a person's quality of life. Therefore, it is necessary to act against it to prevent emotional impact and long\u2010term complications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>This study aimed to demonstrate the efficacy of a chemical peel in combination with a home care\u2010exfoliating and purifying product in improving mild and moderate acne.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The study included 45 patients with mild\u2010to\u2010moderate acne. Patients were treated with a chemical peel containing a mix of salicylic acid, pyruvic acid, and retinoic acid once every 3\u00a0weeks for 4 times, plus a home care treatment after the healing process.<\/jats:p><jats:p>Michaelson's acne severity score, Subject Global Aesthetic Improvement Scale, and Face Skin Q questionnaire were used to evaluate patients\u2019 skin improvement and patients\u2019 satisfaction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All patients have shown improvement in skin lesions after 4\u00a0sessions of chemical peel according to Michaelson's acne severity score and Subject Global Aesthetic Improvement Score. Face Skin Q questionnaire demonstrated an improved quality of life in all treated patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The combination of salicylic acid\u2010based chemical peel plus exfoliating home care treatment appears to be a very good strategy against acne. Therefore, the physician may use this combination as an effective treatment for patients dealing with acne vulgaris.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.14281","type":"journal-article","created":{"date-parts":[[2021,7,28]],"date-time":"2021-07-28T09:42:46Z","timestamp":1627465366000},"page":"2-6","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Efficacy of a combined chemical peel and topical salicylic acid\u2010based gel combination in the treatment of active acne"],"prefix":"10.1111","volume":"20","author":[{"given":"Lucia","family":"Calvisi","sequence":"first","affiliation":[{"name":"Private Practice  Cagliari Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,7,28]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.4103\/0974-2077.129964"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dem108"},{"issue":"8","key":"e_1_2_7_4_1","first-page":"734","article-title":"Diagnosis and treatment of acne","volume":"86","author":"Titus S","year":"2012","journal-title":"Am Fam Physician"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2016.10.011"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/dth.14150"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1210\/edrv.21.4.0404"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.4103\/0974-2077.74500"},{"issue":"8","key":"e_1_2_7_9_1","first-page":"21","article-title":"A Practical Approach to Chemical Peels: A Review of Fundamentals and Step\u2010by\u2010step Algorithmic Protocol for Treatment","volume":"11","author":"Soleymani T","year":"2018","journal-title":"J Clin Aesthet Dermatol"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.1997.tb00003.x"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2011.04374.x"},{"key":"e_1_2_7_12_1","first-page":"S5","article-title":"Standard guidelines of care for chemical peels","volume":"74","author":"Khunger N","year":"2008","journal-title":"Indian J Dermatol Venereol Leprol"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.4103\/0378-6323.51258"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.2012.04335.x"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2003.618"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.2010.03921.x"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.4103\/0974-2077.104913"},{"issue":"7","key":"e_1_2_7_18_1","first-page":"32","article-title":"Evidence and considerations in the application of chemical peels in skin disorders and aesthetic resurfacing","volume":"3","author":"Rendon MI","year":"2010","journal-title":"J Clin Aesthet Dermatol"},{"issue":"2","key":"e_1_2_7_19_1","first-page":"18","article-title":"Alpha\u2010hydroxyacid chemical peeling agents: case studies and rationale for safe and effective use","volume":"73","author":"Briden ME","year":"2004","journal-title":"Cutis"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2006.32075.x"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1159\/000246529"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1524-4725.2002.02107.x"}],"container-title":["Journal of Cosmetic Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.14281","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jocd.14281","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.14281","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,29]],"date-time":"2023-08-29T20:01:27Z","timestamp":1693339287000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jocd.14281"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7]]},"references-count":21,"journal-issue":{"issue":"S2","published-print":{"date-parts":[[2021,7]]}},"alternative-id":["10.1111\/jocd.14281"],"URL":"https:\/\/doi.org\/10.1111\/jocd.14281","archive":["Portico"],"relation":{},"ISSN":["1473-2130","1473-2165"],"issn-type":[{"value":"1473-2130","type":"print"},{"value":"1473-2165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,7]]},"assertion":[{"value":"2021-07-28","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}