{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T02:04:40Z","timestamp":1773799480843,"version":"3.50.1"},"reference-count":25,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2021,6,27]],"date-time":"2021-06-27T00:00:00Z","timestamp":1624752000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Nonsurgical reshaping of the nose, chin, and jawline with hyaluronic acid fillers is becoming increasingly popular. Appropriate patient selection is essential.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To assess the safety and efficacy of nonsurgical treatment of these facial areas using experience\u2010based eligibility criteria and injection of the high G\u2019 filler, VYC\u201025L.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a retrospective analysis of patients undergoing aesthetic improvement of the nose, chin, and\/or jawline with VYC\u201025L, selected based on detailed criteria derived from extensive experience and imaging assessments. In a subgroup of subjects, high\u2010resolution 3D imaging was used to assess nasal angles, nasal hump height, and chin projection.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 135 patients were included (<jats:italic>n<\/jats:italic>\u00a0=\u00a0106 females; mean age, 43.4\u00a0\u00b1\u00a014.3\u00a0years; <jats:italic>n<\/jats:italic>\u00a0=\u00a044 nose treatment only, <jats:italic>n<\/jats:italic>\u00a0=\u00a024 chin\/jawline only, <jats:italic>n<\/jats:italic>\u00a0=\u00a067 both). Mean treatment volume was 3.3\u00a0\u00b1\u00a02.0\u00a0ml. In total, 111 individuals (82.2%) were injected in the nose (mean volume: 0.9\u00a0\u00b1\u00a00.2\u00a0ml) and 91 (67.4%) in the chin\/jawline (mean volume: 3.8\u00a0\u00b1\u00a00.8\u00a0ml). Most complications were injection site\u2010related (bruising, <jats:italic>n<\/jats:italic>\u00a0=\u00a027 [20.0%]; pain, <jats:italic>n<\/jats:italic>\u00a0=\u00a01 [0.7%]). One patient (0.7%) experienced lip herpes, successfully managed with antiviral therapy. Thirty\u2010two individuals underwent 3D imaging, which showed substantial mean changes from baseline in nasofrontal angle (3.5\u00a0\u00b1\u00a01.6 degrees), nasofacial angle (2.2\u00a0\u00b1\u00a00.8 degrees), and nasolabial angle (3.9\u00a0\u00b1\u00a02.6 degrees); decreases in nasal hump height (1.7\u00a0\u00b1\u00a00.9\u00a0mm); and increased chin projection (2.7\u00a0\u00b1\u00a01.5\u00a0mm).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Nonsurgical reshaping of the nose, chin, and jawline was safe and effective using experience\u2010based eligibility criteria and VYC\u201025L.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.14294","type":"journal-article","created":{"date-parts":[[2021,6,15]],"date-time":"2021-06-15T18:44:40Z","timestamp":1623782680000},"page":"1436-1444","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Nonsurgical reshaping of the nose, chin, and jawline: A retrospective analysis using experience\u2010based eligibility criteria"],"prefix":"10.1111","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2027-3749","authenticated-orcid":false,"given":"Lucia","family":"Calvisi","sequence":"first","affiliation":[{"name":"Private practice  Cagliari Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dario","family":"Palazzolo","sequence":"additional","affiliation":[{"name":"InFormaMedica Day Clinic  Palermo Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Triolo","sequence":"additional","affiliation":[{"name":"InFormaMedica Day Clinic  Palermo Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,6,27]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"International Association of Aesthetic Plastic Surgery.ISAPS International survey on aesthetic\/cosmetic procedures performed in 2018.www.isaps.org\/wp\u2010content\/uploads\/2019\/12\/ISAPS\u2010Global\u2010Survey\u2010Results\u20102018\u2010new.pdf. Accessed April 22 2021."},{"key":"e_1_2_10_3_1","unstructured":"American Society of Plastic Surgeons.2019 Plastic Surgery Statistics Report.www.plasticsurgery.org\/documents\/News\/Statistics\/2019\/plastic\u2010surgery\u2010statistics\u2010full\u2010report\u20102019.pdf. 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