{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T09:18:24Z","timestamp":1790068704416,"version":"4.0.1"},"reference-count":32,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2021,7,16]],"date-time":"2021-07-16T00:00:00Z","timestamp":1626393600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Melanocyte\u2010keratinocyte transplant procedure (MKTP) or non\u2010cultured epidermal cell suspension transplantation is a very popular surgical modality for treating stable vitiligo. The recipient\u2010site preparation is one potential determinant in the repigmentation outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>To assess the efficacy of fractional CO<jats:sub>2<\/jats:sub> (FCO<jats:sub>2<\/jats:sub>) laser in recipient\u2010site preparation before MKTP and comparing it to the frequently used full surface laser ablation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This randomized comparative trial included 19 patients with 40 stable vitiligo lesions. In each patient, the treated sites were randomly categorized into two groups according to the recipient\u2010site ablation (either fractional or full ablative CO<jats:sub>2<\/jats:sub> laser). Assessment of repigmentation was performed six months after the procedure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Both modalities achieved successful repigmentation of a median of 80% and 77.5% for fractional and full ablation groups, respectively, with a non\u2010statistically significant difference between them. The median of VASI change percent was \u221273% and \u221271% with fractional and full surface ablation, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>FCO<jats:sub>2<\/jats:sub> laser ablation is effective for recipient\u2010site preparation before cell suspension transplantation as well as the full ablative CO<jats:sub>2<\/jats:sub> laser.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.14324","type":"journal-article","created":{"date-parts":[[2021,7,2]],"date-time":"2021-07-02T14:46:22Z","timestamp":1625237182000},"page":"1506-1513","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Fractional versus full ablative CO<sub>2<\/sub> laser in recipient site of non\u2010cultured melanocytes and keratinocyte transplantation in treatment of vitiligo"],"prefix":"10.1111","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8138-7977","authenticated-orcid":false,"given":"Alzahraa Mohammed","family":"Jamal\u2010edine","sequence":"first","affiliation":[{"name":"Dermatology and Venereology Department Faculty of Medicine for girls Alazhar University  Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2028-3082","authenticated-orcid":false,"given":"Rasha Aly","family":"El\u2010Barbary","sequence":"additional","affiliation":[{"name":"Dermatology and Venereology Department Faculty of Medicine for girls Alazhar University  Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nayera Hassan","family":"Moftah","sequence":"additional","affiliation":[{"name":"Dermatology and Venereology Department Faculty of Medicine for girls Alazhar University  Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,7,16]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2016.10.048"},{"key":"e_1_2_10_3_1","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1111\/ddg.13657","article-title":"The efficacy of ablation\u2010based combination therapy for vitiligo: a systematic review and meta\u2010analysis","volume":"16","author":"King YA","year":"2018","journal-title":"J Dtsch Dermatol Ges"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/exd.12344"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.14356"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.4103\/0974-2077.79192"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/ors.12011"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.4103\/0974-2077.158439"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.det.2016.11.009"},{"key":"e_1_2_10_10_1","first-page":"214","volume-title":"Pigmentary Skin Disorders, Updates in Clinical Dermatology, Lasers in Pigmentary Skin Disorders","author":"Levoska MA","year":"2018"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.4103\/0974-2077.99436"},{"key":"e_1_2_10_12_1","unstructured":"PasseronT.Micro holes for delivering melanocytes in vitiligo skin. 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