{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T14:36:04Z","timestamp":1778942164421,"version":"3.51.4"},"reference-count":40,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Radiofrequency (RF) is a non\u2010invasive or minimally invasive procedure with a low risk of complications. It has been employed for several aesthetic purposes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>This study aimed to conduct a systematic literature review on the use of RF for aesthetic applications and assess the level of accumulated evidence for each condition.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Using the MEDLINE\/PubMed and EMBASE databases, we searched for articles published from 2009 to 2019 describing the use of RF treatment for aesthetic purposes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Our search approach identified 25 randomized clinical trials investigating the efficacy of RF in the following clinical situations: body contour improvement, facial rejuvenation, acne scar treatment, alopecia, and rosacea. There were problems with the quality of the studies, especially regarding selection, performance, and detection bias.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our study revealed that RF treatment is potentially promising in all of the evaluated clinical situations; however, we were not able to identify a level of evidence that justifies its use over other therapeutic options currently available on the market.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.14353","type":"journal-article","created":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T19:28:22Z","timestamp":1627846102000},"page":"2691-2702","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Evaluation of the evidence level for the use of radiofrequency in aesthetic treatments: A systematic review and meta\u2010analysis"],"prefix":"10.1111","volume":"20","author":[{"given":"Andr\u00e9","family":"Oliveira Paggiaro","sequence":"first","affiliation":[{"name":"Plastic Surgery Department S\u00e3o Paulo University S\u00e3o Paulo Brazil"},{"name":"Nursing Post Graduation Guarulhos University Guarulhos, S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafael","family":"Pinheiro","sequence":"additional","affiliation":[{"name":"Nursing Post Graduation Guarulhos University Guarulhos, S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaolanna","family":"Soares","sequence":"additional","affiliation":[{"name":"Nursing Post Graduation Guarulhos University Guarulhos, S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Viviane","family":"Fernandes Carvalho","sequence":"additional","affiliation":[{"name":"Nursing Post Graduation Guarulhos University Guarulhos, S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rolf","family":"Gemperli","sequence":"additional","affiliation":[{"name":"Plastic Surgery Department S\u00e3o Paulo University S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,8]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"Plastic Surgery Statistics Report. 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