{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T00:50:00Z","timestamp":1777942200161,"version":"3.51.4"},"reference-count":30,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2021,9,24]],"date-time":"2021-09-24T00:00:00Z","timestamp":1632441600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Skin\u2010related changes, such as fine lines, wrinkles, and acne scarring, are a source of distress to both men and women. Nanofractional radiofrequency delivers thermal energy to skin layers leading to dermal remodeling that can address skin conditions related to aging. The objective of this study was to evaluate the subject satisfaction of nanofractional radiofrequency for the treatment of facial wrinkles and acne scarring in both lighter and darker skin tones.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>30\u00a0subjects (skin types II\u2010VI) were enrolled in this prospective, evaluator\u2010blind study. The average age of subjects was 51.9\u00a0\u00b1\u00a013.5\u00a0years. Subjects received three treatments at 3\u2010 to 5\u2010week intervals on both sides of the face using the 80\u2010 or the 160\u2010pin tip disposables. Follow\u2010up visits were conducted at 6\u2010 and 12\u00a0weeks after the last treatment. Subject satisfaction was evaluated using a self\u2010assessment of a reduction of wrinkles or acne scars, and subject satisfaction questionnaire. Pain, tolerability, and safety were monitored throughout.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Subjects treated for acne or wrinkles were satisfied with their treatment at both the 6\u2010week and 12\u2010week follow\u2010up visit (mean score 3.0; range 0\u00a0=\u00a0very unsatisfied to 4\u00a0=\u00a0very satisfied). The treatments were well tolerated at all treatment sessions, averaging a score of 3.5 on the tolerability scale (0\u00a0=\u00a0very intolerable to 4\u00a0=\u00a0very tolerable) with treatment\u2010associated pain reported to be mild (3.2 out of 10). There were no adverse events or unanticipated side effects.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This clinical study demonstrates subjects are satisfied with nanofractional radiofrequency treatments for improvement of their wrinkles and acne scars.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.14455","type":"journal-article","created":{"date-parts":[[2021,9,25]],"date-time":"2021-09-25T01:33:03Z","timestamp":1632533583000},"page":"3475-3481","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Subject satisfaction following treatment with nanofractional radiofrequency for the treatment and reduction of acne scarring and rhytids: A prospective study"],"prefix":"10.1111","volume":"20","author":[{"given":"Suleima","family":"Arruda","sequence":"first","affiliation":[{"name":"Department of Dermatology Weill Cornell Medical College New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alyssa","family":"Swearingen","sequence":"additional","affiliation":[{"name":"Department of Dermatology Weill Cornell Medical College New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathleen","family":"Medrano","sequence":"additional","affiliation":[{"name":"Department of Dermatology Weill Cornell Medical College New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9542-4097","authenticated-orcid":false,"given":"Neil","family":"Sadick","sequence":"additional","affiliation":[{"name":"Department of Dermatology Weill Cornell Medical College New York New York USA"},{"name":"Sadick Research Group Sadick Dermatology New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,9,24]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"2018 Plastic Surgery Statistics Report. 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