{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:46:09Z","timestamp":1790729169294,"version":"4.1.0"},"reference-count":23,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2021,9,29]],"date-time":"2021-09-29T00:00:00Z","timestamp":1632873600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>Androgenetic alopecia (AGA) is the most common cause of hair loss in males. Physical examination and history are the most important examinations in diagnosis of the disease. As yet, there is no diagnostic method to be able to determine which individuals will develop AGA. Shear\u2010wave elastography (SWE) is a novel diagnostic tool, which can evaluate tissue stiffness. Superb microvascular imaging (SMI) can determine low flow in microvessels. The aim of the current study was to determine whether or not AGA would develop in individuals with normal hair and a family history of AGA using B\u2010mode US, SMI, and SWE.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The study included 26 patients clinically diagnosed with AGA and a control group of 26 volunteers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Thickness with the distance from the epidermis to the calvarium (ECD) on the hairline and cranial subcutaneous tissue thickness (CSTD) were determined to be statistically significantly thinner in the AGA group than in the control group (<jats:italic>p\u00a0<\/jats:italic>&lt;\u00a00.0001). For the differentiation of the AGA patients, the cutoff value was determined to be 5.5\u00a0mm for ECD and 4.05\u00a0mm for CSTD. The cranial epidermis\u2010dermis (CED) stiffness values both as meter\/second (m\/s) and kilopascals (kPa) were statistically significantly lower in the AGA patients than in the control group (<jats:italic>p\u00a0<\/jats:italic>&lt;\u00a00.0001). The cutoff values were 6.075 as m\/s and 104.4 as kPa.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The results of this study demonstrated that differentiation could be made of individuals before the development of AGA from normal healthy individuals with CSTD measurement on B\u2010mode US and CED stiffness measurement on SWE.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.14488","type":"journal-article","created":{"date-parts":[[2021,9,29]],"date-time":"2021-09-29T23:36:56Z","timestamp":1632958616000},"page":"2962-2970","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["The place of B\u2010mode ultrasonography, shear\u2010wave elastography, and superb microvascular imaging in the pre\u2010diagnosis of androgenetic alopecia"],"prefix":"10.1111","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6536-2780","authenticated-orcid":false,"given":"Bar\u0131\u015f","family":"Ten","sequence":"first","affiliation":[{"name":"Department of Radiology Mersin University Faculty of Medicine  Mersin Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamer \u0130rfan","family":"Kaya","sequence":"additional","affiliation":[{"name":"Department of Dermatology Mersin University Faculty of Medicine  Mersin Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y\u00fcksel","family":"Balc\u0131","sequence":"additional","affiliation":[{"name":"Department of Radiology Mersin University Faculty of Medicine  Mersin Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaan","family":"Esen","sequence":"additional","affiliation":[{"name":"Department of Radiology Mersin University Faculty of Medicine  Mersin Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00fclhan","family":"Temel","sequence":"additional","affiliation":[{"name":"Department of Biostatistics Mersin University Faculty of Medicine  Mersin Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5807-6759","authenticated-orcid":false,"given":"\u00dcmit","family":"T\u00fcrsen","sequence":"additional","affiliation":[{"name":"Department of Dermatology Mersin University Faculty of Medicine  Mersin Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mustafa An\u0131l","family":"Y\u0131lmaz","sequence":"additional","affiliation":[{"name":"Department of Dermatology Mersin University Faculty of Medicine  Mersin Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,9,29]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00105-003-0561-y"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecl.2007.03.004"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12020-017-1280-y"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2003.05565.x"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.4065\/80.10.1316"},{"key":"e_1_2_11_7_1","first-page":"83","volume-title":"Hair loss: principles of diagnosis and management of alopecia","author":"Shapiro 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