{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T07:34:56Z","timestamp":1779176096898,"version":"3.51.4"},"reference-count":18,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2021,10,4]],"date-time":"2021-10-04T00:00:00Z","timestamp":1633305600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Platelet\u2010rich plasma is a useful adjuvant therapy in the treatment of acne scars. Fat is as ideal soft tissue filler.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>To compare the efficacy and safety of subcision with autologous fat grafting versus subcision with intradermal Platelet\u2010rich plasma for the treatment of acne scars.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Twenty\u2010four patients were divided into two groups with 12 patients each. One group subjected to single session of subcision with autologous fat grafting. Second group treated with subcision followed by intradermal Platelet\u2010rich plasma monthly once for 3\u00a0months. High resolution digital photographs taken before and after every session. Single blinded physician assessment was also done.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In quantitative acne scar assessment scoring, both group of patients showed significant percentage of improvement in acne scars, 61.23\u00a0\u00b1\u00a09.48% in patients treated with subcision followed by autologous fat grafting and 44.16\u00a0\u00b1\u00a07.28% in patients treated with subcision followed by intradermal PRP. At the time of enrolment, 33.3% (<jats:italic>n<\/jats:italic>\u00a0=\u00a08) of patients had Grade A (milder) scarring, 50% (<jats:italic>n<\/jats:italic>\u00a0=\u00a012) had Grade B (moderate) scarring while 16.7% (<jats:italic>n<\/jats:italic>\u00a0=\u00a04) had Grade C (severe) scarring. After the completion of the treatment, it was found that 75% (<jats:italic>n<\/jats:italic>\u00a0=\u00a018) of patients were in Grade A while 20.8% (<jats:italic>n<\/jats:italic>\u00a0=\u00a05) of patients were in Grade B (<jats:italic>p\u00a0<\/jats:italic>&lt;\u00a00.05; significant).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Both the treatment modalities, i.e., autologous fat grafting and intradermal PRP were effective and safe for the treatment of acne scars and results in each group was significant (<jats:italic>p\u00a0<\/jats:italic>&lt;\u00a00.001). But there were no statistically significant differences between the two treatment groups (<jats:italic>p\u00a0<\/jats:italic>=\u00a00.23).<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.14503","type":"journal-article","created":{"date-parts":[[2021,10,6]],"date-time":"2021-10-06T05:04:24Z","timestamp":1633496664000},"page":"3454-3461","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["A comparative study of efficacy and safety of autologous fat grafting versus Platelet\u2010rich plasma in the treatment of post\u2010acne scars"],"prefix":"10.1111","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6209-3295","authenticated-orcid":false,"given":"Vinma H.","family":"Shetty","sequence":"first","affiliation":[{"name":"Dermatology AJ Institute of Medical Sciences Mangalore India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanath N.","family":"Bhandary","sequence":"additional","affiliation":[{"name":"Plastic surgery AJ Institute of Medical Sciences Mangalore India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roopa","family":"Bhandary","sequence":"additional","affiliation":[{"name":"Microbiology AJ Institute of Medical Sciences Mangalore India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chintaman","family":"Suvarna","sequence":"additional","affiliation":[{"name":"2nd Year Post Graduate in Dermatology AJ Institute of Medical Sciences Mangalore India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,10,4]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"1","article-title":"Role of adipose\u2010 derived stem cells in chronic cutaneous wound healing","volume":"86","author":"Caruana G","year":"2015","journal-title":"Ann Ital Chir"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2011.01999.x"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2008.05.029"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/DSS.0000000000001765"},{"key":"e_1_2_8_6_1","first-page":"12","article-title":"Acne scarring\u2010 pathogenesis, evaluation and treatment options","volume":"10","author":"Connolly D","year":"2017","journal-title":"J Clin Aesthet Dermatol"},{"key":"e_1_2_8_7_1","first-page":"93","article-title":"Is platelet\u2010rich plasma the perfect enhancement factor? 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