{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T21:33:08Z","timestamp":1767648788556,"version":"3.40.5"},"reference-count":24,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2021,11,3]],"date-time":"2021-11-03T00:00:00Z","timestamp":1635897600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100005795","name":"Chang Gung Memorial Hospital, Linkou","doi-asserted-by":"publisher","award":["CMRPGBJ0021"],"award-info":[{"award-number":["CMRPGBJ0021"]}],"id":[{"id":"10.13039\/501100005795","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Vitiligo is a common, psychologically devastating pigmentary disorder. Surgical graftings are used to treat stable vitiligo when medical treatment fails. An automated epidermal micrograft harvesting (AEMH) system was first designated to treat wounds, and very few studies investigated the application of AEMH in vitiligo. In this study, we investigated the efficacy and safety of the AEMH system in patients with stable segmental and nonsegmental vitiligo. The rate of repigmentation and adverse events was recorded bimonthly for at least 12\u00a0months. We analyzed the efficacy based on patient characteristics, vitiligo subtypes, and different anatomical locations. A total of 56 depigmented lesions from 34 patients were included. 95.50% of the automated epidermal micrografts were successfully grafted at the recipient sites. There was a significant improvement in Vitiligo Area Scoring Index (VASI) and Dermatologic Life Quality Index (DLQI) in patients treated with AEMH (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001). The rate of repigmentation by VASI score improves from 96.25\u00a0\u00b1\u00a08.59 to 48.30\u00a0\u00b1\u00a028.16 after the treatment (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001). Treatment outcomes were comparable between the patients of segmental and stable nonsegmental vitiligo. The face and neck region achieved a better outcome, followed by the trunk (chest, abdomen, back, and axilla), limbs, and the worse outcome was found in the acral region (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.014). Conclusively, AEMH is an effective treatment procedure with limited adverse events in patients with stable vitiligo. This harvesting method may be a feasible option for vitiligo surgical treatment.<\/jats:p>","DOI":"10.1111\/jocd.14548","type":"journal-article","created":{"date-parts":[[2021,11,3]],"date-time":"2021-11-03T17:27:55Z","timestamp":1635960475000},"page":"2924-2930","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Efficacy and safety of automated epidermal micrograft in patients with stable segmental and nonsegmental vitiligo"],"prefix":"10.1111","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9912-5465","authenticated-orcid":false,"given":"Chi\u2010Hui","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Dermatology Chang Gung Memorial Hospital  Taoyuan Taiwan"},{"name":"Department of Biomedical Engineering Chung Yuan Christian University  Chung\u2010Li Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu\u2010Jr","family":"Lin","sequence":"additional","affiliation":[{"name":"Clinical Informatics and Medical Statistics Research Center Chang Gung University  Taoyuan City Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sindy","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Dermatology Chang Gung Memorial Hospital  Taoyuan Taiwan"},{"name":"School of Medicine College of Medicine Chang Gung University  Taoyuan Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yao\u2010Li","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Dermatology Chang Gung Memorial Hospital  Taoyuan Taiwan"},{"name":"School of Medicine College of Medicine Chang Gung University  Taoyuan Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen\u2010Hung","family":"Chung","sequence":"additional","affiliation":[{"name":"Department of Dermatology Chang Gung Memorial Hospital  Taoyuan Taiwan"},{"name":"School of Medicine College of Medicine Chang Gung University  Taoyuan Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7576-963X","authenticated-orcid":false,"given":"Chau Yee","family":"Ng","sequence":"additional","affiliation":[{"name":"Department of Dermatology Chang Gung Memorial Hospital  Taoyuan Taiwan"},{"name":"Graduate Institute of Clinical Medical Sciences Chang Gung University  Taoyuan Taiwan"},{"name":"Vitiligo Clinic and Research Center Chang Gung Memorial Hospital  Linkou 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