{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T01:17:39Z","timestamp":1782782259923,"version":"3.54.5"},"reference-count":9,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2021,11,11]],"date-time":"2021-11-11T00:00:00Z","timestamp":1636588800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2021,12]]},"abstract":"Abstract<\/jats:title>Background<\/jats:title>The effective treatment of melasma remains a challenge that necessitates a multifaceted approach that includes strict sun protection, bleaching creams, chemical peels, and laser therapy. The 1064\u00a0nm Nd:YAG laser with a 650\u2010microsecond pulse duration provides a safe option for all skin types.<\/jats:p><\/jats:sec>Methods<\/jats:title>We treated 10 patients with the 1064\u00a0nm Nd:YAG laser with a 650\u2010microsecond pulse duration. Treatments were performed every 2\u20134\u00a0weeks.<\/jats:p><\/jats:sec>Results<\/jats:title>Using a conservative treatment protocol, lightening of melasma occurred as early as 3\u00a0weeks post\u2010treatment, with all subjects requiring several treatment sessions to achieve adequate resolution of their melasma. The majority of subjects experienced up to 25% improvement after two treatments, and an even more noticeable improvement after the 3rd treatment session. None reported any associated pain or discomfort.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>Advantages of this laser modality include essentially no pain or downtime, lower risk of rebound, and the ability to safely treat all skin types with melasma. Therefore, the 1064\u00a0nm Nd:YAG laser with a 650\u2010microsecond pulse duration serves as a treatment option for melasma.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.14558","type":"journal-article","created":{"date-parts":[[2021,11,11]],"date-time":"2021-11-11T16:24:57Z","timestamp":1636647897000},"page":"3889-3892","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Treating melasma with the 1064\u00a0nm Nd:YAG laser with a 650\u2010microsecond pulse duration: A clinical evaluation"],"prefix":"10.1111","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0273-5241","authenticated-orcid":false,"given":"Tanya","family":"Greywal","sequence":"first","affiliation":[{"name":"Department of Dermatology University of California San Diego San Diego CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arisa","family":"Ortiz","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of California San Diego San Diego CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,11,11]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijwd.2017.01.004"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yacs.2018.02.008"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.15497"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40257-017-0263-3"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/14764172.2017.1376098"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijd.13578"},{"issue":"4","key":"e_1_2_8_8_1","first-page":"s138","article-title":"Practical applications for medical and aesthetic treatment of skin of color with a new 650\u2010microsecond laser","volume":"18","author":"Burgess C","year":"2019","journal-title":"J Drugs Dermatol"},{"issue":"4","key":"e_1_2_8_9_1","first-page":"s135","article-title":"Treatment of skin of color for medical and aesthetic uses with a new 650\u2010microsecond Nd:YAG 1064nm laser","volume":"18","author":"Roberts WE","year":"2019","journal-title":"J Drugs Dermatol"},{"issue":"12","key":"e_1_2_8_10_1","first-page":"s10","article-title":"A novel 0.65 millisecond pulsed 1064 nm laser to treat skin of color without skin cooling or anesthetics","volume":"10","author":"Cook\u2010Bolden F","year":"2011","journal-title":"J Drugs Dermatol"}],"container-title":["Journal of Cosmetic Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.14558","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jocd.14558","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.14558","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,23]],"date-time":"2023-08-23T20:50:12Z","timestamp":1692823812000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jocd.14558"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,11]]},"references-count":9,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["10.1111\/jocd.14558"],"URL":"https:\/\/doi.org\/10.1111\/jocd.14558","archive":["Portico"],"relation":{},"ISSN":["1473-2130","1473-2165"],"issn-type":[{"value":"1473-2130","type":"print"},{"value":"1473-2165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11,11]]},"assertion":[{"value":"2021-08-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-10-13","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-11-11","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}