{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T14:24:41Z","timestamp":1773757481328,"version":"3.50.1"},"reference-count":20,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,11,21]],"date-time":"2021-11-21T00:00:00Z","timestamp":1637452800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Acne scarring can lead to social and psychological distress.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To compare the safety, efficacy, and long\u2010term improvement of subcision using tri\u2010beveled hypodermic (Th) needle versus cannula for the treatment of atrophic post\u2010acne scars.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Forty\u2010six patients with atrophic post\u2010acne scars were treated with subcision using (Th) needle on one side of the face and a blunt cannula on the other side of the face for 6\u00a0sessions one month apart. The primary outcome was based on the clinical improvement and patient satisfaction score. Skin biopsies were taken at baseline and 3months after the final session. Follow\u2010up was 9\u00a0months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Three months after the final session, a statistically highly significant difference was detected in both sides from the baseline (<jats:italic>p\u00a0<\/jats:italic><jats:bold>&lt;\u00a0<\/jats:bold>0.001). The overall improvement was 73.9% on the (Th) needle side versus 65.2% on the cannula side (<jats:italic>p\u00a0<\/jats:italic>=\u00a00.68). There was no significant difference in acne severity scarring grade between both sides (<jats:italic>p\u00a0<\/jats:italic>=\u00a00.86). The mean number of sessions was significantly less in the (Th) needle side (<jats:italic>p\u00a0<\/jats:italic><jats:bold>&lt;\u00a0<\/jats:bold>0.001). Collagen deposition and reorganization were achieved with both modalities. Patient satisfaction showed no significant difference between both sides. The side effects were mild and significantly higher in the (Th) needle side (<jats:italic>p\u00a0<\/jats:italic>=\u00a00.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Both modalities are effective and economic techniques. However, using a cannula is associated with much fewer side effects, more convenient for the patients and physicians compared to the (Th) needle.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.14562","type":"journal-article","created":{"date-parts":[[2021,11,22]],"date-time":"2021-11-22T05:16:34Z","timestamp":1637558194000},"page":"1127-1134","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Clinical and Histopathological evaluation of different tools for the Subcision of Atrophic Acne Scars"],"prefix":"10.1111","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1364-5807","authenticated-orcid":false,"given":"Howyda M.","family":"Ebrahim","sequence":"first","affiliation":[{"name":"Faculty of Medicine Zagazig University  Zagazig Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alyiah Younes","family":"Artima","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Sirte 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