{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T22:53:56Z","timestamp":1785884036731,"version":"3.56.0"},"reference-count":9,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,11,13]],"date-time":"2021-11-13T00:00:00Z","timestamp":1636761600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The Chemical Reconstruction of Skin Scars (CROSS) technique was first described in 2002 and has since demonstrated safety and efficacy in multiple studies. We describe the treatment of six patients with a modified version of the CROSS method\u2014the Painting CROSS trichloroacetic acid (TCA) technique. This technique has the advantage of offering even higher tissue selectivity and better control of the scar edges, enhancing both safety and efficacy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively evaluated 31\u00a0scars of six patients who underwent a single treatment by the Painting CROSS TCA method. A 0.3\u00a0ml insulin syringe with a 30\u2010gauge needle was filled with 0.05\u00a0ml of 85% TCA solution and then applied to the scar base with slight pressure until frosting was achieved. Patients were evaluated before and 3\u00a0months after treatment for scar volume deficit by a high\u2010resolution three\u2010dimensional imaging system.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The average volume of the 31\u00a0scars assessed in our study was 2.71\u00a0mm<jats:sup>3<\/jats:sup> before treatment and 1.96\u00a0mm<jats:sup>3<\/jats:sup> after treatment. There was a 26.3% average decrease in the volume of the scars after one treatment. Transient mild hyperpigmentation was noted in two patients after the treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Painting CROSS TCA technique has demonstrated efficacy in the treatment of acne scars after a single treatment.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.14611","type":"journal-article","created":{"date-parts":[[2021,11,13]],"date-time":"2021-11-13T17:45:56Z","timestamp":1636825556000},"page":"327-330","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Painting CROSS TCA technique: Modification of the CROSS method for the treatment of atrophic acne scars\u2014Case series"],"prefix":"10.1111","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8018-0229","authenticated-orcid":false,"given":"Tamir","family":"Horovitz","sequence":"first","affiliation":[{"name":"Department of Dermatology and Venereology Tel\u2010Aviv Sourasky Medical Center Tel\u2010Aviv Israel"},{"name":"Sackler Faculty of Medicine Tel\u2010Aviv University Tel\u2010Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fares","family":"Salameh","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology Tel\u2010Aviv Sourasky Medical Center Tel\u2010Aviv Israel"},{"name":"Sackler Faculty of Medicine Tel\u2010Aviv University Tel\u2010Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2315-5219","authenticated-orcid":false,"given":"Waseem","family":"Shehadeh","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology Tel\u2010Aviv Sourasky Medical Center Tel\u2010Aviv Israel"},{"name":"Sackler Faculty of Medicine Tel\u2010Aviv University Tel\u2010Aviv 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