{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T01:32:32Z","timestamp":1747186352781,"version":"3.40.5"},"reference-count":14,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,12,13]],"date-time":"2021-12-13T00:00:00Z","timestamp":1639353600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Diode laser (810\u00a0nm) is frequently employed for hair reduction. There are few studies determining the efficacy in Indian population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Assessment of efficacy and safety of 810\u00a0nm diode laser in facial\/axillary hair reduction and objective assessment of the improvement with dermoscopy, photographs, and novel Gabor filter\u2010based hair detection algorithm.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methodology<\/jats:title><jats:p>This hospital\u2010based study included 40 adult women with 108 treatment sites over 5.4\u00a0sessions (range 4\u20138). Evaluation of treatment areas (hair texture, density) was done using modified Ferriman\u2013Galwey scoring. Photography and dermoscopic images were taken before each session and 6\u00a0weeks after the last. Immediate and delayed adverse reactions were noted. Assessment of efficacy was done by patient, principal, and blinded investigator using Global Aesthetic Improvement scale (GAIS) and hair detection algorithm (evaluating characteristics of dermoscopic hair).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The fluences ranged from 16 to 29\u00a0Joules\/cm<jats:sup>2<\/jats:sup> with pulse width of 30\u00a0ms. Upper lip (<jats:italic>n<\/jats:italic>\u00a0=\u00a029, 26.9%) and chin (<jats:italic>n<\/jats:italic>\u00a0=\u00a025, 22.1%) were commonly treated areas. Improvement in hair texture and density (reduction in uniformly distributed, terminal hair from 37.1% to 13.9%) was statistically significant <jats:bold>(<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.0001)<\/jats:bold>. Excellent improvement of 75\u2013100% (GAIS) was noted by principal and blinded investigator in 24.1% and 33.3% total sites, respectively. The median improvement, calculated by the algorithm, was 60% for side locks, 53.9% for axilla, 24.1% for upper lip, and 14.9% for chin. Axilla and upper lip were sites associated with maximum discomfort. Epidermolysis and paradoxical hypertrichosis were seen in five patients each.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The 810\u00a0nm diode laser is safe and effective in the reduction of dark, coarse terminal hairs in Fitzpatrick skin types III\u2013V. Inter\u2010observer variation and investigator bias in the assessment of efficacy can be successfully overcome by using the algorithm.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.14671","type":"journal-article","created":{"date-parts":[[2021,12,14]],"date-time":"2021-12-14T06:00:41Z","timestamp":1639461641000},"page":"1004-1012","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Efficacy of 810\u00a0nm diode laser in hair reduction in Indian subpopulation using a novel Gabor filter\u2010based detection software and hair algorithm"],"prefix":"10.1111","volume":"21","author":[{"given":"Sathish B.","family":"Pai","sequence":"first","affiliation":[{"name":"Department of Dermatology, Venereology and Leprosy Kasturba Medical College, Manipal Academy of Higher Education  Manipal India"},{"name":"Manipal Academy of Higher Education (MAHE)  Manipal India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1095-4310","authenticated-orcid":false,"given":"Punya","family":"Suvarna","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology and Leprosy Kasturba Medical College, Manipal Academy of Higher Education  Manipal India"},{"name":"Manipal Academy of Higher Education (MAHE)  Manipal India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Varsha M.","family":"Shetty","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology and Leprosy Kasturba Medical College, Manipal Academy of Higher Education  Manipal India"},{"name":"Manipal Academy of Higher Education (MAHE)  Manipal India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sameena","family":"Pathan","sequence":"additional","affiliation":[{"name":"Department of Information and Technology Manipal Institute of Technology Manipal Academy of Higher Education (MAHE)  Manipal India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,12,13]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_10_2_1","DOI":"10.1007\/978-3-642-32006-4_1"},{"doi-asserted-by":"publisher","key":"e_1_2_10_3_1","DOI":"10.3109\/14764172.2011.594057"},{"doi-asserted-by":"publisher","key":"e_1_2_10_4_1","DOI":"10.4103\/0974-2077.158445"},{"issue":"11","key":"e_1_2_10_5_1","first-page":"29","article-title":"Efficacy of a low fluence, high repetition rate 810\u00a0nm diode laser for permanent hair reduction in Indian patients with skin types IV\u2010VI","volume":"9","author":"Agarwal M","year":"2016","journal-title":"J Clin Aesthet 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