{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T21:53:31Z","timestamp":1788386011932,"version":"build-2803163510"},"reference-count":25,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2021,12,20]],"date-time":"2021-12-20T00:00:00Z","timestamp":1639958400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Acne scars are one of the most common cosmetic concerns causing psychosocial distress.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the efficacy of subcision versus its combination with either cross\u2010linked hyaluronic acid (HA) or poly\u2010<jats:sc>l<\/jats:sc>\u2010lactic acid (PLLA) threads in the treatment of atrophic post\u2010acne scars.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Forty patients of both genders with atrophic acne scars were subjected to subcision 1\u00a0month apart for 3\u00a0sessions. After the last session of subcision, the patients were reclassified randomly into 2\u00a0equal groups each received either HA or threads in one side of the face leaving the other side that underwent subcision before as a control. Clinical assessment was carried out by the physicians and patients. Photographs and skin biopsies were obtained. Follow\u2010up was 6\u00a0months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A significant clinical improvement was achieved in 67.3% of patients after subcision alone compared to 94.1%, 82.4% of subcision combined with HA or threads, respectively. Patients\u2019 satisfaction was higher in the combined groups compared to subcision alone (<jats:italic>p\u00a0<\/jats:italic>&lt;\u00a00.0001). Side effects were tolerable and transient.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Subcision combined with HA or threads could offer a higher significant clinical improvement of acne scars than subcision alone.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.14675","type":"journal-article","created":{"date-parts":[[2021,12,20]],"date-time":"2021-12-20T08:04:11Z","timestamp":1639987451000},"page":"3334-3342","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["A combined approach of subcision with either cross\u2010linked hyaluronic acid or threads in the treatment of atrophic acne scars"],"prefix":"10.1111","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1364-5807","authenticated-orcid":false,"given":"Howyda M.","family":"Ebrahim","sequence":"first","affiliation":[{"name":"Department of Dermatology Faculty of Medicine Zagazig University  Zagazig Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amany","family":"Nassar","sequence":"additional","affiliation":[{"name":"Department of Dermatology Faculty of Medicine Zagazig University  Zagazig Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamal","family":"ElKashishy","sequence":"additional","affiliation":[{"name":"Department of Pathology Faculty ofMedicine Zagazig University  Zagazig Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aliah Younes Mohamed","family":"Artima","sequence":"additional","affiliation":[{"name":"Department of Dermatology Faculty ofMedicine Sirte University  Sirte Libya"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hala Mohamed","family":"Morsi","sequence":"additional","affiliation":[{"name":"Department of Dermatology Faculty of Medicine Zagazig University  Zagazig 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