{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T05:10:48Z","timestamp":1775625048376,"version":"3.50.1"},"reference-count":24,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2022,1,18]],"date-time":"2022-01-18T00:00:00Z","timestamp":1642464000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Aims<\/jats:title><jats:p>Photomodulation is a non\u2010photothermal effect that mobilizes energy and regulates cell activity at the mitochondrial level, and has been used to treat sensitive skin (SS) in recent years. Based on the photomodulated effect of optimal pulse technology (OPT), we developed a novel treatment mode (advanced OPT with low energy, three pulses, long pulse width, AOPT\u2010LTL) for the treatment of facial SS and evaluated its effectiveness.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of thirty Chinese women with SS were included in this study. Patients were received different times of AOPT\u2010LTL treatment with an interval of 2 to 4\u00a0weeks depending on the severity. Clinical improvement was evaluated by comparing baseline and post\u2010treatment photographs. In addition, the skin objective signs and subjective symptoms, as well as adverse events and patient satisfaction were also analyzed and tabulated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All included patients completed the treatment and follow\u2010up period. After one course of treatment, 76.7% of patients had a Symptom Score Reducing Index (SSRI) &gt;20%, suggesting that the treatment was effective. Within two courses of treatment, all patients had SSRI &gt;20%, demonstrating significant improvement in skin sensitivity. The analysis of clinical photographs showed that facial dryness, desquamation, flushing, and skin color significantly improved, capillary density decreased, the dilated capillaries were retracted. During the treatment period, no obvious adverse reactions occurred in any patients, and the patients\u2019 satisfaction was high.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This novel technique of AOPT\u2010LTL might be an effective and safe modality for the treatment of SS.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.14764","type":"journal-article","created":{"date-parts":[[2022,1,18]],"date-time":"2022-01-18T20:50:46Z","timestamp":1642539046000},"page":"4345-4353","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Effective of a novel technique for sensitive skin treatment with optimal pulse technology: A clinical study"],"prefix":"10.1111","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2128-4618","authenticated-orcid":false,"given":"Jiachen","family":"Yuan","sequence":"first","affiliation":[{"name":"Department of Medical Cosmetology Yanbian University Hospital  Yanji, Jilin China"},{"name":"Department of Dermatology Yanbian University Hospital  Yanji, Jilin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yang","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of Medical Cosmetology Yanbian University Hospital  Yanji, Jilin China"},{"name":"Department of Dermatology Yanbian University Hospital  Yanji, Jilin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhouna","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Medical Cosmetology Yanbian University Hospital  Yanji, Jilin China"},{"name":"Department of Dermatology Yanbian University Hospital  Yanji, Jilin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meilan","family":"Nan","sequence":"additional","affiliation":[{"name":"Department of Medical Cosmetology Yanbian University Hospital  Yanji, Jilin China"},{"name":"Department of Dermatology Yanbian University Hospital  Yanji, Jilin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Dermatology Suzhou Mylike Cosmetic Hospital  Suzhou, Jiangsu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhehu","family":"Jin","sequence":"additional","affiliation":[{"name":"Department of Medical Cosmetology Yanbian University Hospital  Yanji, Jilin China"},{"name":"Department of Dermatology Yanbian University Hospital  Yanji, Jilin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chenglong","family":"Jin","sequence":"additional","affiliation":[{"name":"Department of Medical Cosmetology Yanbian University Hospital  Yanji, Jilin China"},{"name":"Department of Dermatology Suzhou Mylike Cosmetic Hospital  Suzhou, Jiangsu 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