{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T00:30:57Z","timestamp":1789173057334,"version":"build-2803163510"},"reference-count":14,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2022,2,18]],"date-time":"2022-02-18T00:00:00Z","timestamp":1645142400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2022,5]]},"abstract":"Abstract<\/jats:title>\n \n Objectives<\/jats:title>\n Laser therapy has become one of the mainstay treatments for improving\u00a0signs of aging including wrinkles, large pores, and skin pigmentation. However, in patients with pigmented skin, an increase in complications\u00a0including\u00a0post\u2010inflammatory hyperpigmentation (PIH) has been noted. The purpose of\u00a0this\u00a0study is to investigate not only the safety profile of 755\u2010nm\u00a0picosecond laser with\u00a0diffractive lens array (DLA)\u00a0at approximately 2250\u00a0pulses\u00a0on the face\u00a0in people with darker skin, but also to evaluate\u00a0its\u00a0efficacy\u00a0in treating wrinkles and pore sizes\u00a0after one treatment session\u00a0among different age groups.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n This single\u2010center, retrospective study enrolled patients between age 22 and 65 with both facial wrinkles and enlarged pore sizes. A total of 46 patients (7\u00a0male, 39 female, mean age 43) with Fitzpatrick skin types III and IV were enrolled. Two independent data\u2010blinded dermatologists assessed and scored the improvements of patients\u2019 wrinkles and pore sizes using photographs.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n After one\u00a0treatment\u00a0session, statistically significant improvements were observed in lateral canthal wrinkles (\n p<\/jats:italic>\n \u00a0<\u00a00.001) and facial wrinkles (\n p<\/jats:italic>\n \u00a0=\u00a00.014).\u00a0In addition, greater percentage of the patients from the aged group (50\u201365\u00a0years) showed clinically significant improvement as compared with the younger group.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n For patients with\u00a0type III and IV skin,\u00a0one session of DLA\u00a0picosecond laser\u00a0treatment at around 2250 pulses to the face is safe and effective for clinically meaningful improvement of the wrinkles and pore sizes, especially for\u00a0the patients from 50\u2010 to 65\u2010years of age.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/jocd.14810","type":"journal-article","created":{"date-parts":[[2022,1,31]],"date-time":"2022-01-31T15:29:34Z","timestamp":1643642974000},"page":"2026-2030","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Favorable effect after single treatment session of 755\u2010nm\u2010picosecond laser with a diffractive optic lens on facial wrinkles and pore size in Asians"],"prefix":"10.1111","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8316-8444","authenticated-orcid":false,"given":"Yng","family":"Sun","sequence":"first","affiliation":[{"name":"Department of Dermatology Kaohsiung Medical University Hospital Kaohsiung Medical University Kaohsiung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9515-5336","authenticated-orcid":false,"given":"Ting\u2010Ting","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Dermatology Kaohsiung Medical University Hospital Kaohsiung Medical University Kaohsiung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pei\u2010Ling","family":"Chih","sequence":"additional","affiliation":[{"name":"Huang PH Dermatology and Aesthetic Clinic Kaohsiung City Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yin\u2010Chun","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Dermatology Kaohsiung Medical University Hospital Kaohsiung Medical University Kaohsiung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng\u2010Che Eric","family":"Lan","sequence":"additional","affiliation":[{"name":"Department of Dermatology Kaohsiung Medical University Hospital Kaohsiung Medical University Kaohsiung Taiwan"},{"name":"Department of Dermatology College of Medicine Kaohsiung Medical University Kaohsiung 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