{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T21:49:51Z","timestamp":1791496191799,"version":"4.3.4"},"reference-count":17,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2022,4,11]],"date-time":"2022-04-11T00:00:00Z","timestamp":1649635200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2022,4,11]],"date-time":"2022-04-11T00:00:00Z","timestamp":1649635200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Mainly in the past, foreign body complications, including granuloma, were pretty frequent after semi\u2010permanent polymethyl\u2010methacrylate (PMMA) implants.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The authors describe a twenty\u2010year history of recurring post\u2010PMMA complications interspersed by long uneventful years, with acute edematous side effects evolving into unpleasant skin dystrophia with persistent cutis laxa. The case report also discusses a simple clinical algorithm to discriminate among foreign body complications with particular attention to granulomas.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      The authors conclude by discussing the benefits of the anti\u2010dystrophic treatment with natural\u2010origin remodeling PN\u2010HPT\n                      <jats:sup>\u00ae<\/jats:sup>\n                      (Polynucleotides Highly Purified Technology).\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jocd.14950","type":"journal-article","created":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T11:47:54Z","timestamp":1648727274000},"page":"5537-5542","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Clinical commentary about foreign body complications over 20\u00a0years after polymethyl\u2010methacrylate face implants and control of late sequelae with Polynucleotides Highly Purified Technology (PN\u2010HPT\n                    <sup>\u00ae<\/sup>\n                    )"],"prefix":"10.1111","volume":"21","author":[{"given":"Isabella Pia","family":"Palmieri","sequence":"first","affiliation":[{"name":"Master Diploma in Surgery and Aesthetics University of Padua Medical School  Padua Italy"},{"name":"Master Diploma in Aesthetic Medicine University of Naples Medical School  Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2989-1201","authenticated-orcid":false,"given":"Mauro","family":"Raichi","sequence":"additional","affiliation":[{"name":"Clinical Pharmacology and Toxicology Consultant in Aesthetic Medicine  Milan 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