{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:13:38Z","timestamp":1787015618755,"version":"build-2736575974"},"reference-count":31,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2022,4,12]],"date-time":"2022-04-12T00:00:00Z","timestamp":1649721600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Androgenic alopecia is a common genetic disorder that characterized by progressive\u00a0hair follicles and hair atrophy. Despite all available therapeutic techniques, there is low patient satisfaction rate. It seems finding new treatment options for androgenic alopecia is necessary. In the past decade, platelet\u2010rich plasma (PRP), an autologous collection of concentrated platelets with hemostatic and tissue repairing effects, has received developing attention for androgenetic alopecia treatment as a valuable therapeutic technique.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this study, 8 patients suffering from resistance androgenic alopecia\u00a0were enrolled. The PRP and platelet gel were prepared, and a total volume of 10\u00a0cc of the combination of PRP and platelet gel were injected in the scalp androgen\u2010related areas using 23\u2010gauge syringe. The treatment was performed one month and 3\u00a0months after first injection (three times). The hair pull test was done before treatment. The outcome was evaluated 3, 6, and 9\u00a0months after treatment by hair pull test, dermoscopy, photography, and patient's satisfaction.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A significant reduction in hair loss was observed before and after treatment. Hair count (density) increased from average number of 72 (hair\/cm\n                      <jats:sup>2<\/jats:sup>\n                      ) to 210\u00a0hair\/cm\n                      <jats:sup>2<\/jats:sup>\n                      ). Also, the hair diameter was significantly increased before and after treatment for all patients (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.05).\u00a0After the treatment, the pull test was significantly decreased in 8 patients (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study supports the combination therapy of PRP and platelet gel for resistance androgenic alopecia treatment. This technique is an uncomplicated, feasible, and cost\u2010effective treatment option for resistance androgenic alopecia, with high patient satisfaction.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jocd.14963","type":"journal-article","created":{"date-parts":[[2022,4,5]],"date-time":"2022-04-05T03:54:57Z","timestamp":1649130897000},"page":"4307-4312","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Combination of platelet\u2010rich plasma and platelet gel in treatment of resistance androgenic alopecia: A case series study"],"prefix":"10.1111","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5262-0231","authenticated-orcid":false,"given":"Elaheh","family":"Lotfi","sequence":"first","affiliation":[{"name":"Yousef Abad Skin and Hair Center  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Najmeh","family":"Aramianpour","sequence":"additional","affiliation":[{"name":"Kerman University of Medical Sciences  Kerman Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bahareh","family":"Salehi","sequence":"additional","affiliation":[{"name":"Yousef Abad Skin and Hair Center  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,4,12]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00105-003-0561-y"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40257-013-0010-3"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/jpm12030342"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00266-015-0504-x"},{"issue":"6","key":"e_1_2_11_6_1","first-page":"547","article-title":"Technique for producing platelet\u2010rich plasma and platelet 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