{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T03:58:01Z","timestamp":1793332681600,"version":"4.5.0"},"reference-count":25,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2022,6,21]],"date-time":"2022-06-21T00:00:00Z","timestamp":1655769600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Alopecia areata (AA) is an autoimmune disease which causes non\u2010scarring type hair loss considered to target the pigmentary system. The hair follicle may not be the only site for involvement of the disease. Iris, the ciliary body, choroid and epithelium of the retinal pigment may also be affected. The aim of the present study was to compare retinal pigment epithelium (RPE) and choroidal thicknesses between patients with AA and healthy controls.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The study included 44 patients with alopecia areata, and 44\u00a0healthy individuals with similar age and gender distribution. RPE and choroidal thickness measurements were performed through Spectral\u2010domain optical coherence tomography (SD\u2010OCT) (Heidelberg Spectralis<jats:sup>\u00ae<\/jats:sup> OCT).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There was not any significant difference between patients with AA and healthy individuals for RPE and choroidal thickness <jats:italic>(p\u00a0<\/jats:italic>=\u00a00.751, <jats:italic>p\u00a0<\/jats:italic>=\u00a00.725, respectively). However, the choroidal thickness (422\u00a0\u00b1\u00a079\u00a0\u03bcm) was significantly thinner in patients with poor prognostic criteria than other patients (371\u00a0\u00b1\u00a075\u00a0\u03bcm; <jats:italic>p\u00a0<\/jats:italic>=\u00a00.039).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Monitoring of choroidal thicknesses through optic coherence tomography (OCT) may provide an insight for the disease prognosis in patients with AA.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.14975","type":"journal-article","created":{"date-parts":[[2022,4,7]],"date-time":"2022-04-07T18:34:36Z","timestamp":1649356476000},"page":"5098-5102","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Choroidal thickness in patients with alopecia areata: Is it a sign for poor prognosis?"],"prefix":"10.1111","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2319-0807","authenticated-orcid":false,"given":"Tayfun","family":"\u015eahin","sequence":"first","affiliation":[{"name":"Department of Ophthalmology Hitit University Medicine Faculty  Corum Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3669-6631","authenticated-orcid":false,"given":"Aynure","family":"\u00d6ztekin","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hitit University Medicine Faculty  Corum Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,6,21]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.3109\/08916934.2014.910769"},{"key":"e_1_2_10_3_1","first-page":"397","article-title":"Epidemiology and burden of alopecia areata: a systematic review","volume":"8","author":"Villasante Fricke 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