{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,22]],"date-time":"2026-03-22T12:57:18Z","timestamp":1774184238184,"version":"3.50.1"},"reference-count":22,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2022,5,16]],"date-time":"2022-05-16T00:00:00Z","timestamp":1652659200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Removal of the unwanted tattoo was initially focused treatment of picosecond laser in the setting of the unfractionated beam, whereas the fractionated 1064\u2010nm picosecond lasers (Fr\u2010Pico) has been successfully utilized in various skin conditions, including scar and benign pigmented lesions. However, no studies compared the combination of Fr\u2010Pico and unfractional 1064\u2010nm picosecond laser (UFr\u2010Pico) and UFr\u2010Pico alone in tattoo removal.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>This study aims to compare the efficacy and safety of the combination of Fr\u2010Pico and UFr\u2010Pico and the UFr\u2010Pico and in tattoo removal.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>Nineteen black tattoos in 11 patients were treated with UFr\u2010Pico on one half and in combination with Fr\u2010Pico on another half over three sessions with 4\u2010week intervals and 4\u2010week follow\u2010up after the last session. Treatment efficacy was assessed using digital photographs, skin imaging analysis, and patient satisfaction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>After three treatments, tattoo clearance scores revealed that greater than 50% clearance was achieved in 11 (84.6%) tattoos treated with combination side and 9 (69.2%) tattoos with UFr\u2010Pico alone. Significant differences were observed between the groups at 8 and 12\u00a0weeks. Skin textural changes also demonstrated significant improvements in the combination side at Week 12. Adverse events, such as blistering and textural changes, were fewer in the combination side.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The combination of 1064\u00a0nm Fr\u2010Pico and UFr\u2010Pico may be more effective and safer in tattoo removal than UFr\u2010Pico alone.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.15031","type":"journal-article","created":{"date-parts":[[2022,4,30]],"date-time":"2022-04-30T06:59:10Z","timestamp":1651301950000},"page":"2832-2839","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Outcomes of 1064\u2010nm picosecond laser alone and in combination with fractional 1064\u2010nm picosecond laser in tattoo removal"],"prefix":"10.1111","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5107-8153","authenticated-orcid":false,"given":"Punyaphat","family":"Sirithanabadeekul","sequence":"first","affiliation":[{"name":"Department of Dermatology Chulabhorn International College of Medicine Thammasat University  Pathum Thani Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Passaraporn","family":"Vongchansathapat","sequence":"additional","affiliation":[{"name":"Department of Dermatology Chulabhorn International College of Medicine Thammasat University  Pathum Thani Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nalinee","family":"Sutthipisal","sequence":"additional","affiliation":[{"name":"Samitivej Esthetic Institute Samitivej Sukhumvit Hospital  Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5070-5477","authenticated-orcid":false,"given":"Wilai","family":"Thanasarnaksorn","sequence":"additional","affiliation":[{"name":"Samitivej Esthetic Institute Samitivej Sukhumvit Hospital  Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3432-7090","authenticated-orcid":false,"given":"Atchima","family":"Suwanchinda","sequence":"additional","affiliation":[{"name":"Division of Dermatology Faculty of Medicine Ramathibodi Hospital Mahidol University  Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,5,16]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1039\/C8PP00416A"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.23244"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.22540"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.22577"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2014.3045"},{"issue":"11","key":"e_1_2_11_7_1","first-page":"1390","article-title":"A prospective split\u2010face study of the picosecond alexandrite laser with specialized lens array for facial photoaging in Chinese","volume":"15","author":"Ge Y","year":"2016","journal-title":"J Drugs Dermatol"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.22427"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2015.12.010"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/DSS.0000000000000244"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2010.01821.x"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2010.11.005"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.12050"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.20659"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2009.08.051"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/DSS.0000000000002572"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.23197"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/dsu.12104"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2011.07.024"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.4103\/0974-2077.155070"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/DSS.0000000000001257"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2012.2894"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.22391"}],"container-title":["Journal of Cosmetic Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.15031","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jocd.15031","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.15031","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,20]],"date-time":"2023-08-20T21:24:26Z","timestamp":1692566666000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jocd.15031"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,16]]},"references-count":22,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2022,7]]}},"alternative-id":["10.1111\/jocd.15031"],"URL":"https:\/\/doi.org\/10.1111\/jocd.15031","archive":["Portico"],"relation":{},"ISSN":["1473-2130","1473-2165"],"issn-type":[{"value":"1473-2130","type":"print"},{"value":"1473-2165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5,16]]},"assertion":[{"value":"2022-01-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-04-26","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-05-16","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}