{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T21:49:18Z","timestamp":1791496158036,"version":"4.3.4"},"reference-count":13,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2022,7,19]],"date-time":"2022-07-19T00:00:00Z","timestamp":1658188800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2022,7,19]],"date-time":"2022-07-19T00:00:00Z","timestamp":1658188800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Botulinum toxin type A (BoNT\u2010A) injection is a popular cosmetic procedure in East Asian countries, and there are multiple types of toxins on the market. Whether different toxin types induce different changes in the masseter has not been studied.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>We aimed to investigate and compare the changes induced by injection of different types of BoNT\u2010A in the masseter.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Upon retrospective review of clinical records and routine ultrasound examination results of patients who underwent BoNT\u2010A injection, four groups were set for comparison: unapproved toxin, OnabotulinumtoxinA, LanbotulinumtoxinA, and non\u2010injected. Clinical records and ultrasound images were collected. Ultrasound images were taken in both horizontal and coronal planes. Elasticity of the masseter muscle was also investigated by measuring the surface wave speed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 24 patients were included (six patients per group). All patients were young females. For the non\u2010injected group, the deep inferior tendon was clear and the muscle bundles were arranged, with little fibrous content. Patients who received unapproved toxin injection showed highly disarranged muscle and fiber bundles, with much fiber content present. The changes in OnabotulinumtoxinA and LanbotulinumtoxinA groups were in between those in the non\u2010injected and unapproved toxin groups. Muscle rigidity was the highest in the unapproved toxin group, and generally higher in injected groups compared with the non\u2010injected group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Different types of BoNT\u2010A may induce different changes in the masseter.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jocd.15106","type":"journal-article","created":{"date-parts":[[2022,5,23]],"date-time":"2022-05-23T03:21:36Z","timestamp":1653276096000},"page":"5555-5561","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Ultrasonographic observation of the masseter muscle after injection of different botulinum toxin type A"],"prefix":"10.1111","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1978-432X","authenticated-orcid":false,"given":"Zhujun","family":"Li","sequence":"first","affiliation":[{"name":"Peking Union Medical College Hospital of Peking Union Medical College and Chinese Academy of Medical Sciences Department of Plastic Surgery  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zirong","family":"Li","sequence":"additional","affiliation":[{"name":"Peking Union Medical College Hospital of Peking Union Medical College and Chinese Academy of Medical Sciences Department of Plastic Surgery  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1667-7908","authenticated-orcid":false,"given":"Yunzhu","family":"Li","sequence":"additional","affiliation":[{"name":"Peking Union Medical College Hospital of Peking Union Medical College and Chinese Academy of Medical Sciences Department of Plastic Surgery  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruijia","family":"Dong","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, Beijing Tsinghua Changgung Hospital Tsinghua University  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng","family":"Chen","sequence":"additional","affiliation":[{"name":"Peking Union Medical College Hospital of Peking Union Medical College and Chinese Academy of Medical Sciences Department of Ultrasound  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiuzuo","family":"Huang","sequence":"additional","affiliation":[{"name":"Peking Union Medical College Hospital of Peking Union Medical College and Chinese Academy of Medical Sciences Department of Plastic Surgery  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zenan","family":"Xia","sequence":"additional","affiliation":[{"name":"Peking Union Medical College Hospital of Peking Union Medical College and Chinese Academy of Medical Sciences Department of Plastic Surgery  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nanze","family":"Yu","sequence":"additional","affiliation":[{"name":"Peking Union Medical College Hospital of Peking Union Medical College and Chinese Academy of Medical Sciences Department of Plastic Surgery  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0136-2508","authenticated-orcid":false,"given":"Xiao","family":"Long","sequence":"additional","affiliation":[{"name":"Peking Union Medical College Hospital of Peking Union Medical College and Chinese Academy of Medical Sciences Department of Plastic Surgery  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,7,19]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/dss.0000000000001859"},{"key":"e_1_2_10_3_1","unstructured":"Chinese National Medical Products Administration. Accessed July 8 2021.https:\/\/www.nmpa.gov.cn\/index.html"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rehab.2015.06.002"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ca.23337"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.12473"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.12208"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.3390\/toxins12020112"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/01480540701375091"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.25609"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-14997-3"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/jor.21533"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxicon.2019.12.005"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1124\/pr.116.012658"}],"container-title":["Journal of Cosmetic Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.15106","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jocd.15106","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.15106","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T20:52:56Z","timestamp":1791492776000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jocd.15106"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7,19]]},"references-count":13,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2022,11]]}},"alternative-id":["10.1111\/jocd.15106"],"URL":"https:\/\/doi.org\/10.1111\/jocd.15106","archive":["Portico"],"relation":{},"ISSN":["1473-2130","1473-2165"],"issn-type":[{"value":"1473-2130","type":"print"},{"value":"1473-2165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,7,19]]},"assertion":[{"value":"2021-11-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-05-17","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-07-19","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}