{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T21:49:19Z","timestamp":1791496159797,"version":"4.3.4"},"reference-count":12,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2022,6,4]],"date-time":"2022-06-04T00:00:00Z","timestamp":1654300800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2022,6,4]],"date-time":"2022-06-04T00:00:00Z","timestamp":1654300800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To evaluate the efficacy of concentrated growth factor (CGF) injections in patients with androgenic alopecia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Venous blood of 60 patients (aged 18\u201355\u2009years old with a mean age of 38\u2009years) with androgenic alopecia who were treated from September 2017 to September 2019 were collected to prepare CGF. 0.1\u2009ml CGF was injected into the alopecia area with an interval of 30\u201335\u2009days for a total of 6 times. The evaluation was performed before treatment and at 1, 3, and 6\u00a0months after the first injection and 3 and 6\u00a0months after the last injection.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among the 60 patients, 58 cases received 6 treatments completely, 52 cases showed significant improvement, 8 cases improved, and no ineffective or worsening cases were found. Among the 58 patients, hair density, hair follicle density, and hair diameter increased significantly. Furthermore, the hair status of all patients was improved to varying degrees during the 6\u2010month follow\u2010up from the digital photographs. No complications such as redness, swelling, infection, and ulceration were found in the injection area, and the patient satisfaction was 93% (56\/60).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Concentrated growth factor treatment can significantly improve the symptoms of hair loss and increase hair diameter in patients with androgenic alopecia. It is effective, safe, and worth popularizing.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jocd.15109","type":"journal-article","created":{"date-parts":[[2022,5,24]],"date-time":"2022-05-24T10:47:38Z","timestamp":1653389258000},"page":"5723-5729","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Clinical observation and evaluation of\n                    <scp>CGF<\/scp>\n                    in the treatment of androgenic alopecia"],"prefix":"10.1111","volume":"21","author":[{"given":"Fangning","family":"Zhao","sequence":"first","affiliation":[{"name":"The 16th Department, Plastic Surgery Hospital Chinese Academy of Medical Sciences, Peking Union Medical College  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lijun","family":"Hao","sequence":"additional","affiliation":[{"name":"The First Affiliated Hospital of Harbin Medical University  Harbin China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaolei","family":"Jin","sequence":"additional","affiliation":[{"name":"The 16th Department, Plastic Surgery Hospital Chinese Academy of Medical Sciences, Peking Union Medical College  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,6,4]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2003.05565.x"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40778-016-0034-8"},{"issue":"4","key":"e_1_2_10_4_1","first-page":"96","article-title":"Autologous blood preparations rich in platelets, fibrin and growth factors","volume":"8","author":"Fioravanti C","year":"2015","journal-title":"Oral Implantol"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e3182362010"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/DSS.0000000000001049"},{"issue":"6","key":"e_1_2_10_7_1","first-page":"371","article-title":"Hair loss: common causes and treatment","volume":"96","author":"Phillips T","year":"2017","journal-title":"Am Fam Physician"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13555-018-0278-6"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/ID.0000000000000053"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40729-016-0052-4"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.4103\/ams.ams_154_19"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1089\/fpsam.2020.0288"},{"issue":"6","key":"e_1_2_10_13_1","first-page":"1","article-title":"Promising therapies for treating and\/or preventing androgenic alopecia","volume":"17","author":"Mcelwee K","year":"2012","journal-title":"Skin Therapy Lett"}],"container-title":["Journal of Cosmetic Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.15109","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jocd.15109","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.15109","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T20:52:51Z","timestamp":1791492771000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jocd.15109"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6,4]]},"references-count":12,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2022,11]]}},"alternative-id":["10.1111\/jocd.15109"],"URL":"https:\/\/doi.org\/10.1111\/jocd.15109","archive":["Portico"],"relation":{},"ISSN":["1473-2130","1473-2165"],"issn-type":[{"value":"1473-2130","type":"print"},{"value":"1473-2165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,6,4]]},"assertion":[{"value":"2022-03-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-05-18","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-06-04","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}