{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T20:01:20Z","timestamp":1791489680809,"version":"4.3.4"},"reference-count":15,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2022,6,21]],"date-time":"2022-06-21T00:00:00Z","timestamp":1655769600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2022,6,21]],"date-time":"2022-06-21T00:00:00Z","timestamp":1655769600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Fractional microneedling radiofrequency (FMR) has gained popularity for the treatment of acne scars, owing to favorable outcomes and short downtimes. This study aimed to investigate FMR use in reducing facial sebum production and treating acne scars.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>This single\u2010center, prospective, evaluator\u2010blinded trial compared sebum production after three sessions of FMR (Fractora\u00ae 24\u2010pin coated tip) performed one\u2010month apart. Results were evaluated with a sebumeter (Cutometer\u00ae), sebaceous gland histology, and subjects' assessment. Acne scars were graded according to the Echelle d'Evaluation clinique des Cicatrices d'acn\u00e9 scale, Goodman and Baron's qualitative grading system, acne scar volume measurement, and subjects' assessments.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Sebumeter results revealed a significantly decreased (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05) sebum production since the first treatment, sustained throughout the study period. Histological assessment showed decreased density and size of sebaceous glands. The mean acne scar volume decreased significantly, without a significant increase in the mean melanin levels.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Fractora\u00ae 24\u2010pin coated tip can be used as an alternative for patients with acne scars, who wish to concomitantly reduce their facial oiliness. A significant decrease in facial oiliness and acne scars' volume can be seen after a single treatment session, with up to 15.48% decrease in facial oil production.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jocd.15137","type":"journal-article","created":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T05:18:25Z","timestamp":1654060705000},"page":"5872-5879","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["A novel technique in reducing sebum production and improving atrophic acne scars"],"prefix":"10.1111","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5107-8153","authenticated-orcid":false,"given":"Punyaphat","family":"Sirithanabadeekul","sequence":"first","affiliation":[{"name":"Department of Dermatology, Chulabhorn International College of Medicine Thammasat University  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Visanee","family":"Leetrakulwanna","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Chulabhorn International College of Medicine Thammasat University  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3432-7090","authenticated-orcid":false,"given":"Atchima","family":"Suwanchinda","sequence":"additional","affiliation":[{"name":"Division of Dermatology, Faculty of Medicine, Ramathibodi Hospital Mahidol University  Bangkok 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