{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T21:49:24Z","timestamp":1791496164259,"version":"4.3.4"},"reference-count":24,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2022,7,19]],"date-time":"2022-07-19T00:00:00Z","timestamp":1658188800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2022,7,19]],"date-time":"2022-07-19T00:00:00Z","timestamp":1658188800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To observe the efficacy of unilateral subcutaneous injection of botulinum toxin A combined with finasteride and minoxidil in the treatment of androgenic alopecia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Thirty\u2010seven patients with androgenic alopecia were treated with finasteride and minoxidil as standard therapy and were randomly assigned to subcutaneous injections of botulinum toxin A in one hemisphere of the head at the beginning of a 6\u2010month treatment. Before treatment, 3\u00a0months after treatment, and 6\u00a0months after treatment, the patient's head hair growth was photographed and evaluated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      After 3 and 6\u00a0months of treatment, hair density of the treated androgenic alopecia patients was higher than before treatment (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05), and the hair density of the botulinum toxin A injection side was higher than that of the control side (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). After 6\u00a0months of treatment, the response rate of botulinum toxin A combined with finasteride and minoxidil was 77.5%, with no significant side effects observed.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Finasteride and minoxidil have a significant effect on androgenic alopecia, and the effect is further increased after combined with botulinum toxin A subcutaneous injection.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jocd.15179","type":"journal-article","created":{"date-parts":[[2022,6,25]],"date-time":"2022-06-25T04:33:44Z","timestamp":1656131624000},"page":"5584-5590","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["A study of combination unilateral subcutaneous botulinum toxin a treatment for androgenetic alopecia"],"prefix":"10.1111","volume":"21","author":[{"given":"Kai","family":"Tian","sequence":"first","affiliation":[{"name":"Department of Plastic and Aesthetic Surgery the Second Affiliated Hospital of Soochow University  Suzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suyue","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Cosmetic Surgery, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital Gusu School, Nanjing Medical University  Suzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zou","family":"Jia","sequence":"additional","affiliation":[{"name":"Department of Plastic and Aesthetic Surgery the Second Affiliated Hospital of Soochow University  Suzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wushuang","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Plastic and Aesthetic Surgery the Second Affiliated Hospital of Soochow University  Suzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ke","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Plastic and Aesthetic Surgery the First Affiliated Hospital of Soochow University  Suzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7427-0642","authenticated-orcid":false,"given":"Lijun","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Plastic and Aesthetic Surgery the Second Affiliated Hospital of Soochow University  Suzhou 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