{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T01:53:45Z","timestamp":1777600425426,"version":"3.51.4"},"reference-count":37,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2022,7,19]],"date-time":"2022-07-19T00:00:00Z","timestamp":1658188800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>In this study covering all of Turkey, we aimed to define cutaneous and systemic adverse reactions in our patient population after COVID\u201019 vaccination with the Sinovac\/CoronaVac (inactivated SARS\u2010CoV\u20102) and Pfizer\/BioNTech (BNT162b2) vaccines.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This prospective, cross\u2010sectional study included individuals presenting to the dermatology or emergency outpatient clinics of a total of 19 centers after having been vaccinated with the COVID\u201019 vaccines. Systemic, local injection site, and non\u2010local cutaneous reactions after vaccination were identified, and their rates were determined.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 2290 individuals vaccinated between April 15 and July 15, 2021, 2097 (91.6%) received the CoronaVac vaccine and 183 (8%) BioNTech. Systemic reactions were observed at a rate of 31.0% after the first CoronaVac dose, 31.1% after the second CoronaVac dose, 46.4% after the first BioNTech dose, and 46.2% after the second BioNTech dose. Local injection site reactions were detected at a rate of 35.6% after the first CoronaVac dose, 35.7% after the second CoronaVac dose, 86.9% after the first BioNTech dose, and 94.1% after the second BioNTech dose. A total of 133 non\u2010local cutaneous reactions were identified after the CoronaVac vaccine (2.9% after the first dose and 3.5% after the second dose), with the most common being urticaria\/angioedema, pityriasis rosea, herpes zoster, and maculopapular rash. After BioNTech, 39 non\u2010local cutaneous reactions were observed to have developed (24.8% after the first dose and 5% after the second dose), and the most common were herpes zoster, delayed large local reaction, pityriasis rosea, and urticaria\/angioedema in order of frequency. Existing autoimmune diseases were triggered in 2.1% of the patients vaccinated with CoronaVac and 8.2% of those vaccinated with BioNTech.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>There are no comprehensive data on cutaneous adverse reactions specific to the CoronaVac vaccine. We determined the frequency of adverse reactions from the dermatologist's point of view after CoronaVac and BioNTech vaccination and identified a wide spectrum of non\u2010local cutaneous reactions. Our data show that CoronaVac is associated with less harmful reactions while BioNTech may result in more serious reactions, such as herpes zoster, anaphylaxis, and triggering of autoimmunity. However, most of these reactions were self\u2010limiting or required little therapeutic intervention.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.15209","type":"journal-article","created":{"date-parts":[[2022,7,3]],"date-time":"2022-07-03T06:11:56Z","timestamp":1656828716000},"page":"3692-3703","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Cutaneous reactions after <scp>COVID<\/scp>\u201019 vaccination in Turkey: A multicenter study"],"prefix":"10.1111","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9109-3892","authenticated-orcid":false,"given":"Filiz","family":"Cebeci Kahraman","sequence":"first","affiliation":[{"name":"Department of Dermatology \u0130stanbul Medeniyet University, G\u00f6ztepe Prof. Dr. S\u00fcleyman Yal\u00e7\u0131n City Hospital  \u0130stanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4392-4671","authenticated-orcid":false,"given":"Sevil","family":"Sava\u015f Erdo\u011fan","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of Health Sciences, \u0130stanbul Training and Research Hospital  \u0130stanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nurhan D\u00f6ner","family":"Akta\u015f","sequence":"additional","affiliation":[{"name":"Department of Dermatology \u0130zmir Katip \u00c7elebi University, Atat\u00fcrk Training and Research Hospital  \u0130zmir Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H\u00fclya","family":"Albayrak","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Faculty of Medicine Nam\u0131k Kemal University  Tekirda\u011f 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