{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T19:20:08Z","timestamp":1791487208675,"version":"4.3.4"},"reference-count":49,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2022,8,8]],"date-time":"2022-08-08T00:00:00Z","timestamp":1659916800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2022,8,8]],"date-time":"2022-08-08T00:00:00Z","timestamp":1659916800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Acne is one of the most common skin concerns of unknown etiology, often connected to the menstrual cycle in women, and possibly to the microbial profile and function.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>We aimed to investigate how hormonal fluctuation affects hormonal acne\u2010prone skin in different populations in relation to skin clinical parameters and microbial profiles.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We evaluated skin features by using biophysical and topographical tools. For microbial profiling, we sequenced facial skin microbiota and associated the findings with the skin clinical parameters during the different phases of the menstrual cycle.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      We identified differences between and within hormonal phases in women of Chinese and Caucasian origin. Changes were discovered in transepidermal water loss (TEWL), sebum level, hydration level, and pore volume. The most abundant identifiable genera in both ethnicities were\n                      <jats:italic>Cutibacterium<\/jats:italic>\n                      ,\n                      <jats:italic>Staphylococcus<\/jats:italic>\n                      , and\n                      <jats:italic>Streptococcus<\/jats:italic>\n                      , without any significant abundant differences within the menstrual cycle. Interestingly, 11 bacterial metabolic pathways were downregulated in Chinese compared to Caucasian skin during the follicular phase. The majority of these pathways were associated with skin redox balance, perhaps indicating a weaker oxidative stress response in Chinese versus Caucasian skin.\n                      <jats:italic>Novosphingobium<\/jats:italic>\n                      taxa were increased in the Chinese skin microbiome, which has been reported to protect skin from pollution\u2010mediated oxidative stress.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Thus, this pilot study explored some of the clinical and metagenomic changes in acne\u2010prone skin, and provide guidance to tailor\u2010personalized skin care regimes during the menstrual cycle. Also, the skin redox status in acne\u2010prone skin, provides more opportunity to tailor\u2010personalized skin care regimes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jocd.15225","type":"journal-article","created":{"date-parts":[[2022,7,10]],"date-time":"2022-07-10T04:59:31Z","timestamp":1657429171000},"page":"6233-6242","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Clinical and metagenomic profiling of hormonal acne\u2010prone skin in different populations"],"prefix":"10.1111","volume":"21","author":[{"given":"Nina","family":"Hrapovic","sequence":"first","affiliation":[{"name":"Oriflame Cosmetics AB  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2183-857X","authenticated-orcid":false,"given":"Thibaud","family":"Richard","sequence":"additional","affiliation":[{"name":"Oriflame Cosmetics AB  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4948-9949","authenticated-orcid":false,"given":"Cyril","family":"Messaraa","sequence":"additional","affiliation":[{"name":"Oriflame Cosmetics AB  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xi","family":"Li","sequence":"additional","affiliation":[{"name":"Oriflame Cosmetics AB  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Afrouz","family":"Abbaspour","sequence":"additional","affiliation":[{"name":"Department of Medical Epidemiology and Biostatistics Karolinska Institutet  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susanne","family":"Fabre","sequence":"additional","affiliation":[{"name":"Oriflame Cosmetics AB  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alain","family":"Mavon","sequence":"additional","affiliation":[{"name":"Oriflame Cosmetics AB  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bj\u00f6rn","family":"Andersson","sequence":"additional","affiliation":[{"name":"Department of Cellular and molecular Biology (CMB) Karolinska Institutet  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0974-9993","authenticated-orcid":false,"given":"Ia","family":"Khmaladze","sequence":"additional","affiliation":[{"name":"Oriflame Cosmetics AB  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,8,8]]},"reference":[{"key":"e_1_2_14_2_1","unstructured":"ThiyagarajanDK BasitH JeanmonodRPhysiology menstrual cycle;2021. 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