{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T18:54:49Z","timestamp":1791485689484,"version":"4.3.4"},"reference-count":19,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2022,9,20]],"date-time":"2022-09-20T00:00:00Z","timestamp":1663632000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2022,9,20]],"date-time":"2022-09-20T00:00:00Z","timestamp":1663632000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Primary cutaneous amyloidosis (PCA) and post\u2010inflammatory hyperpigmentation (PIH) are common causes of cutaneous hyperpigmentation that are usually diagnosed clinically. However, their presentations are sometimes atypical, and their differentiation is difficult. Dermoscopy is a valuable diagnostic tool for pigmented diseases that might aid in their diagnosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To describe the characteristic dermoscopic features of PCA and PIH together with histopathological correlation, and to differentiate between these conditions in a non\u2010invasive way.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Fifty\u2010two patients with PCA (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a026) and PIH (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a026) were enrolled. A detailed history, skin examination, dermoscopic examination using handheld and video dermoscopy, and histopathological evaluation were performed.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A statistically significant difference could be detected between PCA and PIH in terms of the duration of the disease (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.027), symmetry (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.044), rippling (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), and back affection (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.048). On dermoscopic examination, central hubs were seen more in the PCA group (p\u2009&lt;\u20090.001) with different patterns of peripheral pigmentation. Histopathologically, the number of melanophages per high\u2010power field was significantly higher in the PCA group (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.013).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The results of this study shed the light on the potential of dermoscopy as a non\u2010invasive diagnostic tool in differentiating between doubtful cases of PCA and PIH.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jocd.15332","type":"journal-article","created":{"date-parts":[[2022,8,26]],"date-time":"2022-08-26T05:31:06Z","timestamp":1661491866000},"page":"6434-6440","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Dermoscopy aids in differentiating primary cutaneous amyloidosis and post\u2010inflammatory hyperpigmentation: A clinico\u2010dermoscopic\u2010histopathaological study"],"prefix":"10.1111","volume":"21","author":[{"given":"Solwan I.","family":"El\u2010Samanoudy","sequence":"first","affiliation":[{"name":"Department of Dermatology, Faculty of Medicine Cairo University  Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heba I.","family":"Gawdat","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Faculty of Medicine Cairo University  Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kholoud M.","family":"Fouda","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Faculty of Medicine Cairo University  Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heba Ahmed","family":"Abdelkader","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Faculty of Medicine Cairo University  Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,9,20]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0738-081X(90)90085-F"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40257-021-00620-9"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10103-016-1917-8"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40257-017-0333-6"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/DSS.0000000000000627"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2010.03.001"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1590\/abd1806-4841.20142353"},{"issue":"8","key":"e_1_2_10_9_1","first-page":"WC01","article-title":"Primary cutaneous amyloidosis: a clinical, histopathological and immunofluorescence study","volume":"11","author":"Mehrotra 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