{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T20:44:12Z","timestamp":1791060252198,"version":"4.1.0"},"reference-count":25,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2022,9,20]],"date-time":"2022-09-20T00:00:00Z","timestamp":1663632000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Fractional radiofrequency (FRF) is increasingly used for acne scars. The common coexistence of acne scars and active acne is a challenge in the timely management of acne scarring.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>We conducted a systematic review and meta\u2010analysis to compare the efficacy and safety of FRF treatment with the lasers for acne and\/or acne scars.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A systematic search was performed on PubMed, Embase, Ovid, Cochrane Library, and Web of Science. Compared with the lasers, a meta\u2010analysis was conducted to assess the clinical improvement and adverse events after FRF treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Eight randomized controlled trials were included. FRF group was more effective than the laser group in patient\u2010evaluated acne improvement (RR\u00a0=\u00a01.35, 95% CI: 1.01\u00a0\u223c\u20091.80). Regardless of observer assessment or patient evaluation, the FRF group was as effective as the laser group in treating atrophic acne scars (RR\u00a0=\u00a00.92, 95% CI: 0.78\u00a0\u223c\u20091.08; RR\u2009=1.15, 95% CI: 0.99\u00a0\u223c\u20091.34). Although there was no difference in pain level and crusting time between the two groups (SMD =0.20, 95% CI: \u22120.72\u00a0\u223c\u20091.12; SMD\u00a0=\u00a0\u22120.93, 95% CI: \u22122.38\u00a0\u223c\u20090.52), PIH incidence of FRF was significantly lower than that of the laser group (RR\u00a0=\u00a00.12, 95% CI: 0.04\u00a0\u223c\u20090.35). The duration of erythema after FRF treatment was also obviously shorter than that after the laser treatment (SMD\u00a0=\u00a0\u22120.78, 95% CI: \u22121.37\u00a0\u223c\u00a0\u22120.18). Subgroup analysis showed that at least a 12\u2010week follow\u2010up was required to observe the full effects of FRF.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>FRF could be a better choice for atrophic acne scar patients with active acne. FRF is superior in treating atrophic acne scar patients prone to pigmentation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.15348","type":"journal-article","created":{"date-parts":[[2022,9,5]],"date-time":"2022-09-05T08:24:00Z","timestamp":1662366240000},"page":"6754-6766","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Meta\u2010analysis of fractional radiofrequency treatment for acne and\/or acne scars"],"prefix":"10.1111","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9803-2454","authenticated-orcid":false,"given":"Jing","family":"Li","sequence":"first","affiliation":[{"name":"Department of Dermatology Beijing Jishuitan Hospital Beijing China"},{"name":"Fourth Medical College of Peking University Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fangfang","family":"Duan","sequence":"additional","affiliation":[{"name":"Fourth Medical College of Peking University Beijing China"},{"name":"Clinical Epidemiology Research Center Beijing Jishuitan Hospital Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Kuang","sequence":"additional","affiliation":[{"name":"Department of Dermatology Beijing Jishuitan Hospital Beijing China"},{"name":"Fourth Medical College of Peking University Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,9,20]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n1800"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(11)60321-8"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40257-018-0358-5"},{"issue":"2","key":"e_1_2_10_5_1","first-page":"97","article-title":"Prevalence and risk factors of acne scarring among patients consulting dermatologists in the USA","volume":"16","author":"Tan J","year":"2017","journal-title":"J Drugs Dermatol"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.23484"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.22410"},{"issue":"2","key":"e_1_2_10_8_1","doi-asserted-by":"crossref","first-page":"124","DOI":"10.4103\/JCAS.JCAS_154_19","article-title":"Evidence\u2010based surgical management of post\u2010acne scarring in skin of color","volume":"13","author":"Gupta A","year":"2020","journal-title":"J Cutan Aesthet Surg"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2022.04.022"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/DSS.0000000000002364"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.13299"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40257-019-00451-9"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-151-4-200908180-00135"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.d5928"},{"issue":"3","key":"e_1_2_10_15_1","first-page":"165","article-title":"Comparison of a fractional micro\u2010plasma radio\u2010frequency technology versus fractional ultrapulsed CO2 laser for the treatment of atrophic acne scars","volume":"45","author":"Lu W","year":"2012","journal-title":"Zhonghua Pifuke Zazhi"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.3109\/14764172.2012.720023"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/dsu.12103"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/dsu.12372"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.12139"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.14714"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.36295\/ASRO.2020.231816"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.14071"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00403-015-1601-z"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1080\/14764172.2017.1314507"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.23453"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10103-015-1850-2"}],"container-title":["Journal of Cosmetic Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.15348","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jocd.15348","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.15348","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,3]],"date-time":"2024-10-03T06:24:17Z","timestamp":1727936657000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jocd.15348"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,20]]},"references-count":25,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["10.1111\/jocd.15348"],"URL":"https:\/\/doi.org\/10.1111\/jocd.15348","archive":["Portico"],"relation":{},"ISSN":["1473-2130","1473-2165"],"issn-type":[{"value":"1473-2130","type":"print"},{"value":"1473-2165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9,20]]},"assertion":[{"value":"2022-06-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-08-30","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-09-20","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}